BC002758
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,706 Da
NCBI Official Full Name
Homo sapiens adenosine deaminase, tRNA-specific 1, mRNA
NCBI Official Synonym Full Names
adenosine deaminase, tRNA specific 1
NCBI Official Synonym Symbols
NCBI Protein Information
tRNA-specific adenosine deaminase 1
UniProt Protein Name
tRNA-specific adenosine deaminase 1
UniProt Synonym Protein Names
tRNA-specific adenosine-37 deaminase
UniProt Synonym Gene Names
UniProt Entry Name
ADAT1_HUMAN
NCBI Summary for ADAT1
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
UniProt Comments for ADAT1
ADAT1: Specifically deaminates adenosine-37 to inosine in tRNA- Ala. Belongs to the ADAT1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA processing; Hydrolase; EC 3.5.4.34
Chromosomal Location of Human Ortholog: 16q23.1
Molecular Function: RNA binding; tRNA-specific adenosine deaminase activity
Biological Process: tRNA processing
Research Articles on ADAT1
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Diseases associated with ADAT1 cdna clone
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