BC132824
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,528 Da
NCBI Official Full Name
Homo sapiens arylformamidase, mRNA
NCBI Official Synonym Full Names
arylformamidase
NCBI Official Synonym Symbols
NCBI Protein Information
kynurenine formamidase
UniProt Protein Name
Kynurenine formamidase
UniProt Synonym Protein Names
Arylformamidase
UniProt Synonym Gene Names
UniProt Entry Name
KFA_HUMAN
UniProt Comments for AFMID
AFMID: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. Belongs to the kynurenine formamidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; Hydrolase; Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 3.5.1.9
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: cytoplasm
Molecular Function: hydrolase activity
Biological Process: tryptophan catabolic process to kynurenine
Research Articles on AFMID
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Disclaimer
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Pathways associated with AFMID cdna clone
Diseases associated with AFMID cdna clone
Organs/Tissues associated with AFMID cdna clone
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