BC051377
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,071 Da
NCBI Official Full Name
Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta), mRNA
NCBI Official Synonym Full Names
glycerol-3-phosphate acyltransferase 4
NCBI Official Synonym Symbols
AGPAT6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta [Similar Products]
NCBI Protein Information
glycerol-3-phosphate acyltransferase 4
UniProt Protein Name
Glycerol-3-phosphate acyltransferase 4
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 6; 1-AGP acyltransferase 6; 1-AGPAT 6; Acyl-CoA:glycerol-3-phosphate acyltransferase 4; Lysophosphatidic acid acyltransferase zeta; LPAAT-zeta
UniProt Synonym Gene Names
UniProt Entry Name
GPAT4_HUMAN
NCBI Summary for AGPAT6
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
UniProt Comments for AGPAT6
AGPAT6: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long- chain fatty acyl-CoAs. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein type: Endoplasmic reticulum; EC 2.3.1.15; Membrane protein, integral; Membrane protein, multi-pass; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Transferase; Lipid Metabolism - glycerolipid
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; glycerol-3-phosphate O-acyltransferase activity
Biological Process: acyl-CoA metabolic process; lactation; lipid biosynthetic process; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; triacylglycerol biosynthetic process
Research Articles on AGPAT6
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Pathways associated with AGPAT6 cdna clone
Diseases associated with AGPAT6 cdna clone
Organs/Tissues associated with AGPAT6 cdna clone
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