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AK1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1265716 AK1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AK1, cDNA Clone

 Also Known As   

AK1 cDNA Clone

 Product Gene Name   

AK1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggaagaga agctgaagaa aaccaatatc atctttgtgg tgggtgggcc tggctcaggg aagggcaccc agtgtgagaa gatcgtgcag aagtatggct acacccacct ctccaccggg gacctcctgc ggtccgaggt cagctcaggc tcggccaggg gcaagaagct gtcggaaatc atggagaagg ggcagctggt tccactggag acagtgttgg acatgctccg ggatgccatg gtggccaaag tcaatacttc caaaggcttc ctgattgatg gctacccgcg ggaggtgcag caaggagaag agtttgagcg acggattgga cagcccacac tgctgctgta tgtggacgca ggccctgaga ccatgaccca gcggctcttg aaacgtggag agaccagcgg gcgtgtggac gacaatgagg agaccatcaa aaagcggctg gagacctatt acaaggccac agaacccgtc atcgccttct atgagaaacg tggcattgtg cgcaaggtca acgctgaggg ctccgtggac agtgtcttct cccaggtctg cacccacctg gacgccctaa agtag
 OMIM    103000
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AK1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for AK1. It may not necessarily be applicable to this product.
 NCBI GI #    33876011
 NCBI GeneID    203
 NCBI Accession #    BC001116 [Other Products]
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 UniProt Secondary Accession #    Q9BVK9; Q9UQC7 [Other Products]
 UniProt Related Accession #    P00568 [Other Products]
 Molecular Weight    21,635 Da
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 NCBI Official Full Name    Homo sapiens adenylate kinase 1, mRNA
 NCBI Official Synonym Full Names    adenylate kinase 1
 NCBI Official Symbol    AK1 [Similar Products]
 NCBI Official Synonym Symbols   
HTL-S-58j
[Similar Products]
 NCBI Protein Information    adenylate kinase isoenzyme 1
 UniProt Protein Name    Adenylate kinase isoenzyme 1
 UniProt Synonym Protein Names   
ATP-AMP transphosphorylase 1
 Protein Family    Adenylate kinase
 UniProt Gene Name    AK1 [Similar Products]
 UniProt Synonym Gene Names    AK 1 [Similar Products]
 UniProt Entry Name    KAD1_HUMAN
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 NCBI Summary for AK1    This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
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 UniProt Comments for AK1    AK1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD). Belongs to the adenylate kinase family.

Protein type: Nucleotide Metabolism - purine; Kinase, other; EC 2.7.4.6; EC 2.7.4.3

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: cytoplasm; cytosol

Molecular Function: adenylate kinase activity; nucleoside diphosphate kinase activity

Biological Process: nucleobase, nucleoside and nucleotide interconversion; nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process

Disease: Adenylate Kinase Deficiency, Hemolytic Anemia Due To
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 Research Articles on AK1    1. Studies indicate that the preferred substrate and phosphate donor of all adenylate kinases are AMP and ATP respectively.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AK1 cdna cloneDiseases associated with AK1 cdna clone
 Products by Pathway  Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >20 publications with AK1 and Neoplasms
 Nervous System Diseases Antibodies  >14 publications with AK1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >13 publications with AK1 and Congenital Abnormalities
 Brain Diseases Antibodies  >8 publications with AK1 and Brain Diseases
 Heart Diseases Antibodies  >8 publications with AK1 and Heart Diseases
 Anemia Antibodies  >7 publications with AK1 and Anemia
 Adenylate Kinase Deficiency, Hemolytic Anemia Due To Antibodies  >4 publications with AK1 and Adenylate Kinase Deficiency, Hemolytic Anemia Due To
 Myocardial Ischemia Antibodies  >4 publications with AK1 and Myocardial Ischemia
 Disease Models, Animal Antibodies  >3 publications with AK1 and Disease Models, Animal
 Myocardial Infarction Antibodies  >2 publications with AK1 and Myocardial Infarction
Organs/Tissues associated with AK1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >91 publications with AK1 and Blood
 Muscle Antibodies  >46 publications with AK1 and Muscle
 Heart Antibodies  >19 publications with AK1 and Heart
 Brain Antibodies  >17 publications with AK1 and Brain
 Liver Antibodies  >14 publications with AK1 and Liver
 Nerve Antibodies  >6 publications with AK1 and Nerve
 Kidney Antibodies  >6 publications with AK1 and Kidney
 Vascular Antibodies  >5 publications with AK1 and Vascular
 Embryonic Tissue Antibodies  >4 publications with AK1 and Embryonic Tissue
 Eye Antibodies  >3 publications with AK1 and Eye
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