BC035969
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,160 Da
NCBI Official Full Name
Homo sapiens albumin, mRNA
NCBI Official Synonym Full Names
albumin
NCBI Protein Information
serum albumin
UniProt Protein Name
Serum albumin
UniProt Entry Name
ALBU_HUMAN
NCBI Summary for ALB
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016]
UniProt Comments for ALB
albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Carrier; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; nucleus; protein complex
Molecular Function: chaperone binding; DNA binding; drug binding; fatty acid binding; identical protein binding; oxygen binding; protein binding; pyridoxal phosphate binding; toxin binding
Biological Process: bile acid and bile salt transport; cellular response to starvation; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; maintenance of mitochondrion localization; negative regulation of apoptosis; platelet degranulation; receptor-mediated endocytosis; retinal homeostasis; sodium-independent organic anion transport; transport
Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic
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Pathways associated with ALB cdna clone
Diseases associated with ALB cdna clone
Organs/Tissues associated with ALB cdna clone
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