BC103935
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,244 Da
NCBI Official Full Name
Homo sapiens aldehyde dehydrogenase 1 family, member L2, mRNA
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member L2
NCBI Official Synonym Symbols
NCBI Protein Information
mitochondrial 10-formyltetrahydrofolate dehydrogenase
UniProt Protein Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 1 member L2
UniProt Synonym Gene Names
UniProt Entry Name
AL1L2_HUMAN
NCBI Summary for ALDH1L2
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
UniProt Comments for ALDH1L2
ALDH1L2: a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
Protein type: Oxidoreductase; EC 1.5.1.6
Chromosomal Location of Human Ortholog: 12q23.3
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity; formyltetrahydrofolate dehydrogenase activity
Biological Process: folic acid metabolic process
Research Articles on ALDH1L2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with ALDH1L2 cdna clone
Organs/Tissues associated with ALDH1L2 cdna clone
|