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AMACR cdna clone

Scan QR to view Datasheet Catalog #    MBS1273980 AMACR cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AMACR, cDNA Clone

★Popular Item★
 Also Known As   

AMACR cDNA Clone

 Product Gene Name   

AMACR cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcactgc agggcatctc ggtcatggag ctgtccggcc tggccccggg cccgttctgt gctatggtcc tggctgactt cggggcgcgt gtggtacgcg tggaccggcc cggctcccgc tacgacgtga gccgcttggg ccggggcaag cgctcgctag tgctggacct gaagcagccg cggggagccg ccgtgctgcg gcgtctgtgc aagcggtcgg atgtgctgct ggagcccttc cgccgcggtg tcatggagaa actccagctg ggcccagaga ttctgcagcg ggaaaatcca aggcttattt atgccaggct gagtggattt ggccagtcag gaagcttctg ccggttagct ggccacgata tcaactattt ggctttgtca ggtggaagga acagcatatt taagttcttt tctgtggaaa actcagaaat cgagtctgtg ggaagcacct cgaggacaga acatgttgga tggtggagca cctttctata cgacttacag gacagcagat ggggaattca tggctgttgg agcaatagaa ccccagttct acgagctgct gatcaaagga cttggactaa agtctga
 OMIM    214950
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of AMACR cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for AMACR. It may not necessarily be applicable to this product.
 NCBI GI #    14495718
 NCBI GeneID    23600
 NCBI Accession #    BC009471 [Other Products]
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 UniProt Secondary Accession #    O43673; Q3KT79; Q96GH1; Q9Y3Q1; A5YM47; B8Y916; B8Y918; F8W9N1 [Other Products]
 UniProt Related Accession #    Q9UHK6 [Other Products]
 Molecular Weight    43,860 Da
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 NCBI Official Full Name    Homo sapiens alpha-methylacyl-CoA racemase, mRNA
 NCBI Official Synonym Full Names    alpha-methylacyl-CoA racemase
 NCBI Official Symbol    AMACR [Similar Products]
 NCBI Official Synonym Symbols   
RM; RACE; CBAS4; AMACRD
[Similar Products]
 NCBI Protein Information    alpha-methylacyl-CoA racemase
 UniProt Protein Name    Alpha-methylacyl-CoA racemase
 UniProt Synonym Protein Names   
2-methylacyl-CoA racemase
 Protein Family    Alpha-methylacyl-CoA racemase
 UniProt Gene Name    AMACR [Similar Products]
 UniProt Entry Name    AMACR_HUMAN
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 NCBI Summary for AMACR    This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
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 UniProt Comments for AMACR    AMACR: Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Belongs to the CaiB/BaiF CoA-transferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.1.99.4; Isomerase; Lipid Metabolism - primary bile acid biosynthesis; Mitochondrial

Chromosomal Location of Human Ortholog: 5p13

Cellular Component: cytoplasm; mitochondrion; peroxisomal matrix; peroxisome

Molecular Function: alpha-methylacyl-CoA racemase activity; receptor binding

Biological Process: bile acid biosynthetic process; bile acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase

Disease: Alpha-methylacyl-coa Racemase Deficiency; Bile Acid Synthesis Defect, Congenital, 4
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 Research Articles on AMACR    1. AMACRwas not regulated in the white blood cells of multiple sclerosis patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AMACR cdna cloneDiseases associated with AMACR cdna clone
 Products by Pathway  Pathway Diagram
 Beta-oxidation Of Pristanoyl-CoA Pathway antibodies  Beta-oxidation Of Pristanoyl-CoA Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Bile Acid Biosynthesis, Cholesterol => Cholate Pathway antibodies  Bile Acid Biosynthesis, Cholesterol => Cholate Pathway Diagram
 Bile Acid Biosynthesis, Cholesterol => Cholate Pathway antibodies  Bile Acid Biosynthesis, Cholesterol => Cholate Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Primary Bile Acid Biosynthesis Pathway antibodies  Primary Bile Acid Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >264 publications with AMACR and Neoplasms
 Prostatic Neoplasms Antibodies  >189 publications with AMACR and Prostatic Neoplasms
 Carcinoma Antibodies  >177 publications with AMACR and Carcinoma
 Adenocarcinoma Antibodies  >144 publications with AMACR and Adenocarcinoma
 Kidney Neoplasms Antibodies  >42 publications with AMACR and Kidney Neoplasms
 Kidney Diseases Antibodies  >40 publications with AMACR and Kidney Diseases
 Hyperplasia Antibodies  >32 publications with AMACR and Hyperplasia
 Adenoma Antibodies  >29 publications with AMACR and Adenoma
 Colorectal Neoplasms Antibodies  >27 publications with AMACR and Colorectal Neoplasms
 Breast Neoplasms Antibodies  >11 publications with AMACR and Breast Neoplasms
Organs/Tissues associated with AMACR cdna clone
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >201 publications with AMACR and Prostate
 Kidney Antibodies  >43 publications with AMACR and Kidney
 Blood Antibodies  >33 publications with AMACR and Blood
 Lung Antibodies  >11 publications with AMACR and Lung
 Liver Antibodies  >10 publications with AMACR and Liver
 Bladder Antibodies  >9 publications with AMACR and Bladder
 Intestine Antibodies  >8 publications with AMACR and Intestine
 Lymph Antibodies  >8 publications with AMACR and Lymph
 Lymph Node Antibodies  >7 publications with AMACR and Lymph Node
 Muscle Antibodies  >5 publications with AMACR and Muscle
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