BC062701
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,954 Da
NCBI Official Full Name
Homo sapiens aquaporin 7, mRNA
NCBI Official Synonym Full Names
aquaporin 7
NCBI Protein Information
aquaporin-7
UniProt Protein Name
Aquaporin-7
UniProt Synonym Protein Names
Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like
UniProt Synonym Gene Names
UniProt Entry Name
AQP7_HUMAN
NCBI Summary for AQP7
This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015]
UniProt Comments for AQP7
AQP7: Forms a channel for water and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Transporter, aquaporin family; Transporter; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9p13
Cellular Component: cytoplasm; integral to plasma membrane; intercellular junction; plasma membrane
Molecular Function: glycerol channel activity; urea transmembrane transporter activity; water channel activity
Biological Process: cellular water homeostasis; excretion; generation of precursor metabolites and energy; glycerol transport; water transport
Disease: Glycerol Quantitative Trait Locus
Research Articles on AQP7
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with AQP7 cdna clone
Diseases associated with AQP7 cdna clone
Organs/Tissues associated with AQP7 cdna clone
|