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ARFGAP1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1271945 ARFGAP1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   


 Product Gene Name   

ARFGAP1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggccagcc caagaaccag gaaggttctt aaagaagtca gggtgcagga tgagaacaac gtttgttttg agtgtggcgc gttcaatcct cagtgggtca gtgtgaccta cggcatctgg atctgcctgg agtgctcggg gagacaccgc gggcttgggg ttcacctcag ctttgtgcgc tctgttacta tggacaagtg gaaggacatt gagcttgaga agatgaaagc tggtgggaat gctaagttcc gagagttcct ggagtctcag gaggattacg atccttgctg gtccttgcag gagaagtaca acagcagagc cgcggccctc tttagggata aggtggtcgc tctggccgaa ggcagagagt ggtctctgga gtcatcacct gcccagaact ggaccccacc tcagcccagg acgctgccgt ccatggtgca ccgagtctct ggccagccgc agagtgtgac cgcctcctcg gacaaggctt ttgaagactg gctgaatgat gacctcggct cctatcaagg ggcccagggg aatcgctacg tggggtttgg gaacacgcca ccgcctcaga agaaagaaga tgacttcctc aacaacgcca tgtcctccct gtactcgggc tggagcagct tcaccactgg agccagccgg tttgcctcgg cagccaagga gggcgctaca aagtttggat cccaagcgag tcagaagttt tggggtcaca agcagcagcc ggagccggcg tccgagctgg gccacagcct gaacgagaac gtcctcaagc ctgcgcagga gaaggtgaag gagggaaaga tttttgatga tgtctccagt ggggtctctc agttggcgtc caagggagtc ggtagtaagg gatggcggga cgtcaccacc tttttttcgg ggaaagcaga gggccccttg gacagcccct cggagggcca cagttatcag aacagcggtc tggaccactt ccaaaacagc aacatagacc agagcttctg ggagaccttt ggaagtgctg agcccaccaa gacccgcaag tccccgagca gcgacagctg gacgtgcgcg gacacctcca ccgagaggag gagctcggac agctgggagg tgtggggctc ggcctccacc aacaggaaca gcaacagcga cggcggggag ggcggggagg gcaccaagaa ggcagtgccg ccggccgtgc ccactgatga tggctgggac aaccagaact ggtag
 OMIM    608377
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ARFGAP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ARFGAP1. It may not necessarily be applicable to this product.
 NCBI GI #    20381345
 NCBI GeneID    55738
 NCBI Accession #    BC028233 [Other Products]
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 UniProt Secondary Accession #    Q6PK71; Q96KC4; Q96T02; Q9NSU3; Q9NVF6; Q9UIL0; B7Z3U0; B7Z8H8; B7ZBI3; E1P5I9; E7EV62 [Other Products]
 UniProt Related Accession #    Q8N6T3 [Other Products]
 Molecular Weight    39,705 Da
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 NCBI Official Full Name    Homo sapiens ADP-ribosylation factor GTPase activating protein 1, mRNA
 NCBI Official Synonym Full Names    ADP ribosylation factor GTPase activating protein 1
 NCBI Official Symbol    ARFGAP1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    ADP-ribosylation factor GTPase-activating protein 1
 UniProt Protein Name    ADP-ribosylation factor GTPase-activating protein 1
 UniProt Synonym Protein Names   
ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
 Protein Family    ADP-ribosylation factor GTPase-activating protein
 UniProt Gene Name    ARFGAP1 [Similar Products]
 UniProt Synonym Gene Names    ARF1GAP; ARF GAP 1; ARF1 GAP [Similar Products]
 UniProt Entry Name    ARFG1_HUMAN
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 NCBI Summary for ARFGAP1    The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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 UniProt Comments for ARFGAP1    ARF GAP1: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cytosol

Molecular Function: GTPase activator activity; protein binding

Biological Process: ER to Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER
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 Research Articles on ARFGAP1    1. ARFGAP1 is found associated with lipid droplets at steady state in some but not all hepatocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ARFGAP1 cdna cloneDiseases associated with ARFGAP1 cdna clone
 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Arf1 Pathway antibodies  Arf1 Pathway Diagram
 COPI Mediated Transport Pathway antibodies  COPI Mediated Transport Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Golgi To ER Retrograde Transport Pathway antibodies  Golgi To ER Retrograde Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Unfolded Protein Response Pathway antibodies  Unfolded Protein Response Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with ARFGAP1 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with ARFGAP1 and Brain Diseases
 Seizures Antibodies  >1 publications with ARFGAP1 and Seizures
 Developmental Disabilities Antibodies  >1 publications with ARFGAP1 and Developmental Disabilities
Organs/Tissues associated with ARFGAP1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with ARFGAP1 and Nerve
 Blood Antibodies  >3 publications with ARFGAP1 and Blood
 Brain Antibodies  >3 publications with ARFGAP1 and Brain
 Liver Antibodies  >2 publications with ARFGAP1 and Liver
 Heart Antibodies  >2 publications with ARFGAP1 and Heart
 Testis Antibodies  >2 publications with ARFGAP1 and Testis
 Ovary Antibodies  >1 publications with ARFGAP1 and Ovary
 Lung Antibodies  >1 publications with ARFGAP1 and Lung
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