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ARHGAP29 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274934 ARHGAP29 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARHGAP29, cDNA Clone

★Popular Item★
 Also Known As   

ARHGAP29 cDNA Clone

 Product Gene Name   

ARHGAP29 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgattgctc acaaacagaa aaagacaaag aaaaaacgtg cttgggcatc aggtcaactc tctactgata ttacaacttc tgaaatgggg ctcaagtcct taagttccaa ctctattttt gatccggatt acatcaagga gttggtgaat gatatcagga agttctccca catgttacta tatttgaaag aagccatatt ttcagactgt tttaaagaag ttattcatat acgtctagag gaactgctcc gtgttttaaa gtctataatg aataaacatc agaacctcaa ttctgttgat cttcaaaatg ctgcagaaat gctcactgca aaagtgaaag ctgtgaactt cacagaagtt aatgaagaaa acaaaaacga tctcttccag gaagtgtttt cttctattga aactttggca tttacctttg gaaatatcct tacaaacttc cttatgggag atgtaggcaa tgattcatta ttgcgactgc ctgtttctcg agaaactaag tcgtttgaaa atgtttctgt ggaatcagtg gactcatcca gtgaaaaagg aaatttttcc cctttagaac tagacaacgt gctgttaaag aacactgact ctatcgagct ggctttgtca tatgctaaaa cttggtcaaa atatactaag aacatagttt catgggttga aaaaaagctt aacttggaat tggagtccac tagaaatatg gtcaagttgg cagaggcaac tagaactaac attggaattc aggagttcat gccactgcag tctctgttta ctaatgctct tcttaatgat atagaaagca gtcacctttt acaacaaaca attgcagctc tccaggctaa caaatttgtg cagcctctac ttggaaggaa aaatgaaatg gaaaaacaaa ggaaagaaat aaaagagctt tggaaacagg agcaaaataa aatgcttgaa gcagagaatg ctctcaaaaa ggcaaaatta ttatgcatgc aacgtcaaga tgaatatgag aaagcaaagt cttccatgtt tcgtgcagaa gaggagcatc tgtcttcaag tggcggatta gcaaaaaatc tcaacaagca actagaaaaa aagcgaaggt tggaagagga ggctctccaa aaagtaacga tctttttctt ttttatttgc aagttgaatt ag
 OMIM    610496
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ARHGAP29 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ARHGAP29. It may not necessarily be applicable to this product.
 NCBI GI #    18490366
 NCBI GeneID    9411
 NCBI Accession #    BC022483 [Other Products]
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 UniProt Secondary Accession #    O15463; Q59H86; Q5VYZ0; Q6NVX2; Q8TBI6 [Other Products]
 UniProt Related Accession #    Q52LW3 [Other Products]
 Molecular Weight    45,194 Da
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 NCBI Official Full Name    Homo sapiens Rho GTPase activating protein 29, mRNA
 NCBI Official Synonym Full Names    Rho GTPase activating protein 29
 NCBI Official Symbol    ARHGAP29 [Similar Products]
 NCBI Official Synonym Symbols   
PARG1
[Similar Products]
 NCBI Protein Information    rho GTPase-activating protein 29
 UniProt Protein Name    Rho GTPase-activating protein 29
 UniProt Synonym Protein Names   
PTPL1-associated RhoGAP protein 1; Rho-type GTPase-activating protein 29
 Protein Family    Rho GTPase-activating protein
 UniProt Gene Name    ARHGAP29 [Similar Products]
 UniProt Synonym Gene Names    PARG1 [Similar Products]
 UniProt Entry Name    RHG29_HUMAN
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 NCBI Summary for ARHGAP29    Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]
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 UniProt Comments for ARHGAP29    ARHGAP29: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activator activity; PDZ domain binding

Biological Process: regulation of small GTPase mediated signal transduction; Rho protein signal transduction
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 Research Articles on ARHGAP29    1. Data indicate that through GTPase-activating proteins ArhGAP29 complex formation Rap1 GTP-binding protein spatially restricts Rho-mediated signaling, which is necessary for endothelial barrier potentiation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ARHGAP29 cdna cloneDiseases associated with ARHGAP29 cdna clone
 Products by Pathway  Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with ARHGAP29 and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with ARHGAP29 and Cell Transformation, Neoplastic
 Lymphoma, Mantle-Cell Antibodies  >2 publications with ARHGAP29 and Lymphoma, Mantle-Cell
 Colonic Neoplasms Antibodies  >1 publications with ARHGAP29 and Colonic Neoplasms
 Breast Neoplasms Antibodies  >1 publications with ARHGAP29 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with ARHGAP29 and Neoplasms, Experimental
Organs/Tissues associated with ARHGAP29 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with ARHGAP29 and Nerve
 Bone Antibodies  >1 publications with ARHGAP29 and Bone
 Vascular Antibodies  >1 publications with ARHGAP29 and Vascular
 Lung Antibodies  >1 publications with ARHGAP29 and Lung
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