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ATF3 cdna clone

Scan QR to view Datasheet Catalog #    MBS1274107 ATF3 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATF3, cDNA Clone

★Popular Item★
 Also Known As   

ATF3 cDNA Clone

 Product Gene Name   

ATF3 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgatgcttc aacacccagg ccaggtctct gcctcggaag tgagtgcttc tgccatcgtc ccctgcctgt cccctcctgg gtcactggtg tttgaggatt ttgctaacct gacgcccttt gtcaaggaag agctgaggtt tgccatccag aacaagcacc tctgccaccg gatgtcctct gcgctggaat cagtcactgt cagcgacaga cccctcgggg tgtccatcac aaaagccgag gtagcccctg aagaagatga aaggaaaaag aggcgacgag aaagaaataa gattgcagct gcaaagtgcc gaaacaagaa gaaggagaag acggagtgcc tgcagaaaga gtcggagaag ctggaaagtg tgaatgctga actgaaggct cagattgagg agctcaagaa cgagaagcag catttgatat acatgctcaa ccttcatcgg cccacgtgta ttgtccgggc tcagaatggg aggactccag aagatgagag aaacctcttt atccaacaga taaaagaagg aacattgcag agctaa
 OMIM    603148
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ATF3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ATF3. It may not necessarily be applicable to this product.
 NCBI GI #    33871560
 NCBI GeneID    467
 NCBI Accession #    BC006322 [Other Products]
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 UniProt Secondary Accession #    Q5VTZ2; Q6ICQ9; Q7Z566; Q8WYM6 [Other Products]
 UniProt Related Accession #    P18847 [Other Products]
 Molecular Weight    14,314 Da
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 NCBI Official Full Name    Homo sapiens activating transcription factor 3, mRNA
 NCBI Official Synonym Full Names    activating transcription factor 3
 NCBI Official Symbol    ATF3 [Similar Products]
 NCBI Protein Information    cyclic AMP-dependent transcription factor ATF-3
 UniProt Protein Name    Cyclic AMP-dependent transcription factor ATF-3
 UniProt Synonym Protein Names   
Activating transcription factor 3
 Protein Family    Activating transcription factor
 UniProt Gene Name    ATF3 [Similar Products]
 UniProt Synonym Gene Names    cAMP-dependent transcription factor ATF-3 [Similar Products]
 UniProt Entry Name    ATF3_HUMAN
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 NCBI Summary for ATF3    This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]
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 UniProt Comments for ATF3    ATF-3: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Belongs to the bZIP family. ATF subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: nucleolus; nucleoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription corepressor activity; transcription factor activity

Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter
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 Research Articles on ATF3    1. CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ATF3 cdna cloneDiseases associated with ATF3 cdna clone
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 PERK Regulated Gene Expression Pathway antibodies  PERK Regulated Gene Expression Pathway Diagram
 Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >144 publications with ATF3 and Neoplasms
 Nervous System Diseases Antibodies  >118 publications with ATF3 and Nervous System Diseases
 Pain Antibodies  >86 publications with ATF3 and Pain
 Inflammation Antibodies  >72 publications with ATF3 and Inflammation
 Peripheral Nervous System Diseases Antibodies  >58 publications with ATF3 and Peripheral Nervous System Diseases
 Necrosis Antibodies  >41 publications with ATF3 and Necrosis
 Drug Toxicity Antibodies  >40 publications with ATF3 and Drug Toxicity
 Cardiovascular Diseases Antibodies  >38 publications with ATF3 and Cardiovascular Diseases
 Nerve Degeneration Antibodies  >23 publications with ATF3 and Nerve Degeneration
 Liver Diseases Antibodies  >22 publications with ATF3 and Liver Diseases
Organs/Tissues associated with ATF3 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >142 publications with ATF3 and Nerve
 Ganglia Antibodies  >105 publications with ATF3 and Ganglia
 Brain Antibodies  >74 publications with ATF3 and Brain
 Blood Antibodies  >72 publications with ATF3 and Blood
 Liver Antibodies  >53 publications with ATF3 and Liver
 Muscle Antibodies  >48 publications with ATF3 and Muscle
 Bone Antibodies  >39 publications with ATF3 and Bone
 Skin Antibodies  >36 publications with ATF3 and Skin
 Lung Antibodies  >34 publications with ATF3 and Lung
 Pancreas Antibodies  >32 publications with ATF3 and Pancreas
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