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ATP6V0C cdna clone

Scan QR to view Datasheet Catalog #    MBS1273643 ATP6V0C cdna clone
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATP6V0C, cDNA Clone

 Also Known As   

ATP6V0C cDNA Clone

 Product Gene Name   

ATP6V0C cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    108745
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ATP6V0C cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ATP6V0C. It may not necessarily be applicable to this product.
 NCBI GI #    33873673
 NCBI GeneID    527
 NCBI Accession #    BC007759 [Other Products]
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 UniProt Secondary Accession #    Q6FH26 [Other Products]
 UniProt Related Accession #    P27449 [Other Products]
 Molecular Weight    15,736 Da
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 NCBI Official Full Name    Homo sapiens ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c, mRNA
 NCBI Official Synonym Full Names    ATPase H+ transporting V0 subunit c
 NCBI Official Symbol    ATP6V0C [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    V-type proton ATPase 16 kDa proteolipid subunit
 UniProt Protein Name    V-type proton ATPase 16 kDa proteolipid subunit
 UniProt Synonym Protein Names   
Vacuolar proton pump 16 kDa proteolipid subunit
 UniProt Gene Name    ATP6V0C [Similar Products]
 UniProt Synonym Gene Names    ATP6C; ATP6L; ATPL; V-ATPase 16 kDa proteolipid subunit [Similar Products]
 UniProt Entry Name    VATL_HUMAN
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 NCBI Summary for ATP6V0C    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010]
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 UniProt Comments for ATP6V0C    ATP6V0C: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase proteolipid subunit family.

Protein type: Transporter, ion channel; Transporter, iron; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: endosome membrane; focal adhesion; lysosomal membrane; phagocytic vesicle membrane

Molecular Function: hydrogen ion transporting ATP synthase activity, rotational mechanism; hydrogen ion transporting ATPase activity, rotational mechanism; protein binding; ubiquitin protein ligase binding

Biological Process: insulin receptor signaling pathway; lysosomal lumen acidification; positive regulation of Wnt receptor signaling pathway; proton transport; transferrin transport
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 Research Articles on ATP6V0C    1. Data show that 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9) inhibit cell growth by regulating expression of KLF4/LASS2/V-ATPase proteins in breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ATP6V0C cdna cloneDiseases associated with ATP6V0C cdna clone
 Products by Pathway  Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Collecting Duct Acid Secretion Pathway antibodies  Collecting Duct Acid Secretion Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Insulin Receptor Recycling Pathway antibodies  Insulin Receptor Recycling Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway antibodies  Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with ATP6V0C and Disease Models, Animal
Organs/Tissues associated with ATP6V0C cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with ATP6V0C and Brain
 Nerve Antibodies  >2 publications with ATP6V0C and Nerve
 Eye Antibodies  >2 publications with ATP6V0C and Eye
 Connective Tissue Antibodies  >1 publications with ATP6V0C and Connective Tissue
 Bone Antibodies  >1 publications with ATP6V0C and Bone
 Embryonic Tissue Antibodies  >1 publications with ATP6V0C and Embryonic Tissue
 Prostate Antibodies  >1 publications with ATP6V0C and Prostate
 Lung Antibodies  >1 publications with ATP6V0C and Lung
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