BC021965
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,119 Da
NCBI Official Full Name
Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1, mRNA
NCBI Official Synonym Full Names
beta-1,4-glucuronyltransferase 1
NCBI Official Synonym Symbols
iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI [Similar Products]
NCBI Protein Information
beta-1,4-glucuronyltransferase 1
UniProt Protein Name
Beta-1,4-glucuronyltransferase 1
UniProt Synonym Protein Names
I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
UniProt Synonym Gene Names
UniProt Entry Name
B4GA1_HUMAN
NCBI Summary for B3GNT1
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]
UniProt Comments for B3GNT1
B4GAT1: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.
Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - keratan sulfate biosynthesis; EC 2.4.1.149; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: Golgi apparatus; Golgi membrane
Molecular Function: glucuronosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
Biological Process: keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; protein amino acid O-linked mannosylation
Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 13
Research Articles on B3GNT1
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Pathways associated with B3GNT1 cdna clone
Organs/Tissues associated with B3GNT1 cdna clone
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