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BAG2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1269691 BAG2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BAG2, cDNA Clone

 Also Known As   

BAG2 cDNA Clone

 Product Gene Name   

BAG2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    ATGGCTCAGG CGAAGATCAA CGCTAAAGCC AACGAGGGGC GCTTCTGCCG CTCCTCCTCC ATGGCTGACC GCTCCAGCCG CCTGCTGGAG AGCCTGGACC AGCTGGAGCT CAGGGTTGAA GCTTTGAGAG AAGCAGCAAC TGCTGTTGAG CAAGAGAAAG AAATCCTTCT GGAAATGATC CACAGTATCC AAAATAGCCA GGACATGAGG CAGATCAGTG ACGGAGAAAG AGAAGAATTA AATCTGACTG CAAACCGTTT GATGGGAAGA ACTCTCACCG TTGAAGTGTC AGTAGAAACA ATTAGAAACC CCCAGCAGCA AGAATCCCTA AAGCATGCCA CAAGGATTAT TGATGAGGTG GTCAATAAGT TTCTGGATGA TTTGGGAAAT GCCAAGAGTC ATTTAATGTC GCTCTACAGT GCATGTTCAT CTGAGGTGCC ACATGGGCCA GTTGATCAGA AGTTTCAATC CATAGTAATT GGCTGTGCTC TTGAAGATCA GAAGAAAATT AAGAGAAGAT TAGAGACTCT GCTTAGAAAT ATTGAAAACT CTGACAAGGC CATCAAGCTA TTAGAGCATT CTAAAGGAGC TGGTTCCAAA ACTCTGCAAC AAAATGCTGA AAGCAGATTC AATTAG
 OMIM    603882
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of BAG2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for BAG2. It may not necessarily be applicable to this product.
 NCBI GI #    115528699
 NCBI GeneID    9532
 NCBI Accession #    BC125039 [Other Products]
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 UniProt Secondary Accession #    Q08AS9; Q6FID0; B4DXE2 [Other Products]
 UniProt Related Accession #    O95816 [Other Products]
 Molecular Weight    20,189 Da
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 NCBI Official Full Name    Homo sapiens BCL2-associated athanogene 2, mRNA
 NCBI Official Synonym Full Names    BCL2 associated athanogene 2
 NCBI Official Symbol    BAG2 [Similar Products]
 NCBI Official Synonym Symbols   
BAG-2; dJ417I1.2
[Similar Products]
 NCBI Protein Information    BAG family molecular chaperone regulator 2
 UniProt Protein Name    BAG family molecular chaperone regulator 2
 UniProt Synonym Protein Names   
Bcl-2-associated athanogene 2
 Protein Family    BAG family molecular chaperone regulator
 UniProt Gene Name    BAG2 [Similar Products]
 UniProt Synonym Gene Names    BAG-2 [Similar Products]
 UniProt Entry Name    BAG2_HUMAN
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 NCBI Summary for BAG2    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BAG2    BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 6p12.1-p11.2

Cellular Component: cytosol

Molecular Function: adenyl-nucleotide exchange factor activity; identical protein binding; protein binding

Biological Process: protein folding; protein metabolic process
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 Research Articles on BAG2    1. NF-kappaB-mediated modulation of BAG2 expression regulates the shift between the neurotrophic and neurotoxic effects of Abeta1-42.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BAG2 cdna cloneDiseases associated with BAG2 cdna clone
 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with BAG2 and Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with BAG2 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >2 publications with BAG2 and Liver Neoplasms
 Fibrosis Antibodies  >2 publications with BAG2 and Fibrosis
 Liver Neoplasms, Experimental Antibodies  >2 publications with BAG2 and Liver Neoplasms, Experimental
 Brain Diseases Antibodies  >2 publications with BAG2 and Brain Diseases
 Liver Diseases Antibodies  >2 publications with BAG2 and Liver Diseases
 Necrosis Antibodies  >2 publications with BAG2 and Necrosis
 Prenatal Injuries Antibodies  >1 publications with BAG2 and Prenatal Injuries
 Cell Transformation, Neoplastic Antibodies  >1 publications with BAG2 and Cell Transformation, Neoplastic
Organs/Tissues associated with BAG2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >123 publications with BAG2 and Muscle
 Embryonic Tissue Antibodies  >14 publications with BAG2 and Embryonic Tissue
 Liver Antibodies  >3 publications with BAG2 and Liver
 Bone Antibodies  >1 publications with BAG2 and Bone
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