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BCAT1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1267580 BCAT1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BCAT1, cDNA Clone

 Also Known As   

BCAT1 cDNA Clone

 Product Gene Name   

BCAT1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggattgca gtaacggatg ctccgcagag tgtaccggag aaggaggatc aaaagaggtg gtggggactt ttaaggctaa agacctaata gtcacaccag ctaccatttt aaaggaaaaa ccagacccca ataatctggt ttttggaact gtgttcacgg atcatatgct gacggtggag tggtcctcag agtttggatg ggagaaacct catatcaagc ctcttcagaa cctgtcattg caccctggct catcagcttt gcactatgca gtggaattat ttgaaggatt gaaggcattt cgaggagtag ataataaaat tcgactgttt cagccaaacc tcaacatgga tagaatgtat cgctctgctg tgagggcaac tctgccggta tttgacaaag aagagctctt agagtgtatt caacagcttg tgaaattgga tcaagaatgg gtcccatatt caacatctgc tagtctgtat attcgtccta cattcattgg aactgagcct tctcttggag tcaagaagcc taccaaagcc ctgctctttg tactcttgag cccagtggga ccttattttt caagtggaac ctttaatcca gtgtccctgt gggccaatcc caagtatgta agagcctgga aaggtggaac tggggactgc aagatgggag ggaattacgg ctcatctctt tttgcccaat gtgaagcagt agataatggg tgtcagcagg tcctgtggct ctatggagag gaccatcaga tcactgaagt gggaactatg aatctttttc tttactggat aaatgaagat ggagaagaag aactggcaac tcctccacta gatggcatca ttcttccagg agtgacaagg cggtgcattc tggacctggc acatcagtgg gacacagaac tcagcttgtt ttcaattaat ttgcctgatt ttctgcagtt catttacttt tga
 OMIM    113520
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of BCAT1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for BCAT1. It may not necessarily be applicable to this product.
 NCBI GI #    21707321
 NCBI GeneID    586
 NCBI Accession #    BC033864 [Other Products]
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 UniProt Secondary Accession #    Q68DQ7; Q96MY9; B3KY27; B7Z2M5; B7Z5L0; F5H5E4 [Other Products]
 UniProt Related Accession #    P54687 [Other Products]
 Molecular Weight    44,131 Da
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 NCBI Official Full Name    Homo sapiens branched chain aminotransferase 1, cytosolic, mRNA
 NCBI Official Synonym Full Names    branched chain amino acid transaminase 1
 NCBI Official Symbol    BCAT1 [Similar Products]
 NCBI Official Synonym Symbols   
BCT1; PP18; BCATC; ECA39; MECA39; PNAS121
[Similar Products]
 NCBI Protein Information    branched-chain-amino-acid aminotransferase, cytosolic
 UniProt Protein Name    Branched-chain-amino-acid aminotransferase, cytosolic
 UniProt Synonym Protein Names   
Protein ECA39
 Protein Family    Branched-chain-amino-acid aminotransferase
 UniProt Gene Name    BCAT1 [Similar Products]
 UniProt Synonym Gene Names    BCT1; ECA39; BCAT(c) [Similar Products]
 UniProt Entry Name    BCAT1_HUMAN
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 NCBI Summary for BCAT1    This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
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 UniProt Comments for BCAT1    BCAT1: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.6.1.42; Transferase

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: cytosol; mitochondrion

Molecular Function: branched-chain-amino-acid transaminase activity; pyridoxal phosphate binding

Biological Process: aspartate biosynthetic process; branched chain family amino acid biosynthetic process; branched chain family amino acid catabolic process; cell proliferation; G1/S transition of mitotic cell cycle; leucine biosynthetic process; valine biosynthetic process
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 Research Articles on BCAT1    1. BCAT1 is strongly overexpressed in ovarian cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BCAT1 cdna cloneDiseases associated with BCAT1 cdna clone
 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Branched-chain Amino Acid Catabolism Pathway antibodies  Branched-chain Amino Acid Catabolism Pathway Diagram
 Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies  Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
 Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway antibodies  Leucine Degradation, Leucine => Acetoacetate + Acetyl-CoA Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Pantothenate And CoA Biosynthesis Pathway antibodies  Pantothenate And CoA Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >3 publications with BCAT1 and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >2 publications with BCAT1 and Ovarian Neoplasms
 Liver Diseases Antibodies  >2 publications with BCAT1 and Liver Diseases
 Cardiovascular Diseases Antibodies  >2 publications with BCAT1 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >2 publications with BCAT1 and Adenocarcinoma
 Inflammation Antibodies  >2 publications with BCAT1 and Inflammation
 Brain Diseases Antibodies  >1 publications with BCAT1 and Brain Diseases
 Hypertension Antibodies  >1 publications with BCAT1 and Hypertension
 Fatty Liver Antibodies  >1 publications with BCAT1 and Fatty Liver
 Hyperplasia Antibodies  >1 publications with BCAT1 and Hyperplasia
Organs/Tissues associated with BCAT1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with BCAT1 and Blood
 Vascular Antibodies  >5 publications with BCAT1 and Vascular
 Brain Antibodies  >4 publications with BCAT1 and Brain
 Muscle Antibodies  >3 publications with BCAT1 and Muscle
 Heart Antibodies  >3 publications with BCAT1 and Heart
 Liver Antibodies  >2 publications with BCAT1 and Liver
 Testis Antibodies  >2 publications with BCAT1 and Testis
 Ovary Antibodies  >1 publications with BCAT1 and Ovary
 Eye Antibodies  >1 publications with BCAT1 and Eye
 Thyroid Antibodies  >1 publications with BCAT1 and Thyroid
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