BC016661
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,240 Da
NCBI Official Full Name
Homo sapiens butyrophilin, subfamily 2, member A1, mRNA
NCBI Official Synonym Full Names
butyrophilin subfamily 2 member A1
NCBI Official Synonym Symbols
BTF1; BT2.1; BTN2.1; DJ3E1.1; BK14H9.1 [Similar Products]
NCBI Protein Information
butyrophilin subfamily 2 member A1
UniProt Protein Name
Butyrophilin subfamily 2 member A1
UniProt Synonym Gene Names
UniProt Entry Name
BT2A1_HUMAN
NCBI Summary for BTN2A1
This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
UniProt Comments for BTN2A1
BTN2A1: a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: integral to plasma membrane
Biological Process: lipid metabolic process
Research Articles on BTN2A1
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Diseases associated with BTN2A1 cdna clone
Organs/Tissues associated with BTN2A1 cdna clone
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