BC038294
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,293 Da
NCBI Official Full Name
Homo sapiens chromosome 10 open reading frame 46, mRNA
NCBI Official Synonym Full Names
CDK2 associated cullin domain 1
NCBI Protein Information
CDK2-associated and cullin domain-containing protein 1
UniProt Protein Name
CDK2-associated and cullin domain-containing protein 1
UniProt Synonym Protein Names
Cdk-associated cullin1
UniProt Synonym Gene Names
UniProt Entry Name
CACL1_HUMAN
UniProt Comments for C10orf46
CACUL1: Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. Belongs to the cullin family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 10q26.11
Cellular Component: anaphase-promoting complex
Molecular Function: protein binding; protein kinase binding; ubiquitin protein ligase binding
Biological Process: G1/S transition of mitotic cell cycle; positive regulation of cell proliferation; positive regulation of protein kinase activity; protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on C10orf46
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Diseases associated with C10orf46 cdna clone
Organs/Tissues associated with C10orf46 cdna clone
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