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CALM1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1278587 CALM1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CALM1, cDNA Clone

★Popular Item★
 Also Known As   

CALM1 cDNA Clone

 Product Gene Name   

CALM1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctgatc agctgaccga agaacagatt gctgaattca aggaagcctt ctccctattt gataaagatg gcgatggcac catcacaaca aaggaacttg gaactgtcat gaggtcactg ggtcagaacc caacagaagc tgaattgcag gatatgatca atgaagtgga tgctgatggt aatggcacca ttgacttccc cgaatttttg actatgatgg ctagaaaaat gaaagataca gatagtgaag aagaaatccg tgaggcattc cgagtctttg acaaggatgg caatggttat atcagtgcag cagaactacg tcacgtcatg acaaacttag gagaaaaact aacagatgaa gaagtagatg aaatgatcag agaagcagat attgatggag acggacaagt caactatgaa gaattcgtac agatgatgac tgcaaaatga
 OMIM    114180
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CALM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CALM1. It may not necessarily be applicable to this product.
 NCBI GI #    33875466
 NCBI GeneID    801
 NCBI Accession #    BC000454 [Other Products]
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 UniProt Secondary Accession #    P02593; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3 [Other Products]
 UniProt Related Accession #    P62158 [Other Products]
 Molecular Weight    16,838 Da
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 NCBI Official Full Name    Homo sapiens calmodulin 1 (phosphorylase kinase, delta), mRNA
 NCBI Official Synonym Full Names    calmodulin 1
 NCBI Official Symbol    CALM1 [Similar Products]
 NCBI Official Synonym Symbols   
caM; CAMI; PHKD; CPVT4; DD132; LQT14; CALML2
[Similar Products]
 NCBI Protein Information    calmodulin
 UniProt Protein Name    Calmodulin
 Protein Family    Calmodulin
 UniProt Gene Name    CALM1 [Similar Products]
 UniProt Synonym Gene Names    CALM; CAM; CAM1; CaM [Similar Products]
 UniProt Entry Name    CALM_HUMAN
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 NCBI Summary for CALM1    This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
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 UniProt Comments for CALM1    Calmodulin: a calcium-binding small regulatory protein that mediates the control of a large number of enzymes by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Has four functional calcium-binding domains. Phosphorylation and ubiquitination result in a decreased activity.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 14q32.11

Cellular Component: centrosome; cytoplasm; cytosol; extracellular region; nucleoplasm; nucleus; plasma membrane; sarcomere; spindle microtubule; spindle pole; vesicle

Molecular Function: calcium ion binding; inositol trisphosphate 3-kinase activity; ligand-gated ion channel activity; N-terminal myristoylation domain binding; phospholipase binding; protein binding; protein domain specific binding; protein kinase binding; protein serine/threonine kinase activator activity; Ras guanyl-nucleotide exchange factor activity; thioesterase binding; titin binding

Biological Process: detection of calcium ion; G-protein coupled receptor protein signaling pathway; glycogen catabolic process; inositol phosphate metabolic process; MAPKKK cascade; muscle contraction; platelet degranulation; positive regulation of cyclic nucleotide metabolic process; positive regulation of cyclic-nucleotide phosphodiesterase activity; positive regulation of phosphoprotein phosphatase activity; positive regulation of protein amino acid autophosphorylation; positive regulation of protein amino acid dephosphorylation; regulation of cytokinesis; regulation of heart rate; regulation of nitric-oxide synthase activity; regulation of rhodopsin mediated signaling; response to calcium ion; substantia nigra development; Wnt receptor signaling pathway, calcium modulating pathway

Disease: Long Qt Syndrome 14; Ventricular Tachycardia, Catecholaminergic Polymorphic, 4
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 Research Articles on CALM1    1. These findings suggest that lysoPC induces CaM phosphorylation at Tyr(99) by a Src family kinase and that phosphorylated CaM activates PI3K to produce PIP3, which promotes TRPC6 translocation to the cell membrane.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CALM1 cdna cloneDiseases associated with CALM1 cdna clone
 Products by Pathway  Pathway Diagram
 Activation Of Ca-permeable Kainate Receptor Pathway antibodies  Activation Of Ca-permeable Kainate Receptor Pathway Diagram
 Activation Of CaMK IV Pathway antibodies  Activation Of CaMK IV Pathway Diagram
 Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies  Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >7 publications with CALM1 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >3 publications with CALM1 and Drug Toxicity
 Fibrosis Antibodies  >3 publications with CALM1 and Fibrosis
 Neoplasms Antibodies  >3 publications with CALM1 and Neoplasms
 Disease Models, Animal Antibodies  >2 publications with CALM1 and Disease Models, Animal
 Brain Diseases Antibodies  >2 publications with CALM1 and Brain Diseases
 Atrophy Antibodies  >1 publications with CALM1 and Atrophy
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with CALM1 and Prenatal Exposure Delayed Effects
 Phencyclidine Abuse Antibodies  >1 publications with CALM1 and Phencyclidine Abuse
 Marijuana Abuse Antibodies  >1 publications with CALM1 and Marijuana Abuse
Organs/Tissues associated with CALM1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >9 publications with CALM1 and Muscle
 Heart Antibodies  >7 publications with CALM1 and Heart
 Bone Antibodies  >6 publications with CALM1 and Bone
 Blood Antibodies  >5 publications with CALM1 and Blood
 Brain Antibodies  >5 publications with CALM1 and Brain
 Nerve Antibodies  >2 publications with CALM1 and Nerve
 Parathyroid Antibodies  >1 publications with CALM1 and Parathyroid
 Pancreas Antibodies  >1 publications with CALM1 and Pancreas
 Embryonic Tissue Antibodies  >1 publications with CALM1 and Embryonic Tissue
 Intestine Antibodies  >1 publications with CALM1 and Intestine
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