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CCL14 cdna clone

Scan QR to view Datasheet Catalog #    MBS1275415 CCL14 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CCL14, cDNA Clone

★Popular Item★
 Also Known As   

CCL14 cDNA Clone

 Product Gene Name   

CCL14 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgaagatct ccgtggctgc cattcccttc ttcctcctca tcaccatcgc cctagggacc aagactgaat cctcctcacg gggaccttac cacccctcag agtgctgctt cacctacact acctacaaga tcccgcgtca gcggattatg gattactatg agaccaacag ccagtgctcc aagcccggaa ttgtcttcat caccaaaagg ggccattccg tctgtaccaa ccccagtgac aagtgggtcc aggactatat caaggacatg aaggagaact ga
 OMIM    601392
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CCL14 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CCL14. It may not necessarily be applicable to this product.
 NCBI GI #    23468311
 NCBI GeneID    6358
 NCBI Accession #    BC038289 [Other Products]
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 UniProt Secondary Accession #    Q13954; E1P649; E1P650 [Other Products]
 UniProt Related Accession #    Q16627 [Other Products]
 Molecular Weight    12,297 Da
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 NCBI Official Full Name    Homo sapiens chemokine (C-C motif) ligand 14, mRNA
 NCBI Official Synonym Full Names    C-C motif chemokine ligand 14
 NCBI Official Symbol    CCL14 [Similar Products]
 NCBI Official Synonym Symbols   
CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 14
 UniProt Protein Name    C-C motif chemokine 14
 UniProt Synonym Protein Names   
Chemokine CC-1/CC-3; HCC-1/HCC-3
 Protein Family    C-C motif chemokine
 UniProt Gene Name    CCL14 [Similar Products]
 UniProt Synonym Gene Names    NCC2; SCYA14; HCC-1/HCC-3 [Similar Products]
 UniProt Entry Name    CCL14_HUMAN
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 NCBI Summary for CCL14    This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]
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 UniProt Comments for CCL14    CCL14: Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q12

Molecular Function: CCR chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of cell proliferation; positive regulation of GTPase activity; positive regulation of inflammatory response
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 Research Articles on CCL14    1. CCL2, 3, 14 have roles in stimulating macrophage bone marrow homing, proliferation, and polarization in multiple myeloma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CCL14 cdna cloneDiseases associated with CCL14 cdna clone
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >4 publications with CCL14 and Carcinoma
 Kidney Diseases Antibodies  >2 publications with CCL14 and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with CCL14 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with CCL14 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >1 publications with CCL14 and Ovarian Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with CCL14 and Neoplasms, Experimental
Organs/Tissues associated with CCL14 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with CCL14 and Liver
 Kidney Antibodies  >2 publications with CCL14 and Kidney
 Spleen Antibodies  >2 publications with CCL14 and Spleen
 Muscle Antibodies  >1 publications with CCL14 and Muscle
 Heart Antibodies  >1 publications with CCL14 and Heart
 Intestine Antibodies  >1 publications with CCL14 and Intestine
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