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CCL22 cdna clone

Scan QR to view Datasheet Catalog #    MBS1271351 CCL22 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CCL22, cDNA Clone

★Popular Item★
 Also Known As   

CCL22 cDNA Clone

 Product Gene Name   

CCL22 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctcgcc tacagactgc actcctggtt gtcctcgtcc tccttgctgt ggcgcttcaa gcaactgagg caggccccta cggcgccaac atggaagaca gcgtctgctg ccgtgattac gtccgttacc gtctgcccct gcgcgtggtg aaacacttct actggacctc agactcctgc ccgaggcctg gcgtggtgtt gctaaccttc agggataagg agatctgtgc cgatcccaga gtgccctggg tgaagatgat tctcaataag ctgagccaat ga
 OMIM    602957
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CCL22 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CCL22. It may not necessarily be applicable to this product.
 NCBI GI #    20380789
 NCBI GeneID    6367
 NCBI Accession #    BC027952 [Other Products]
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 UniProt Secondary Accession #    A0N0Q6; B2R4W2 [Other Products]
 UniProt Related Accession #    O00626 [Other Products]
 Molecular Weight    10,625 Da
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 NCBI Official Full Name    Homo sapiens chemokine (C-C motif) ligand 22, mRNA
 NCBI Official Synonym Full Names    C-C motif chemokine ligand 22
 NCBI Official Symbol    CCL22 [Similar Products]
 NCBI Official Synonym Symbols   
MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 22
 UniProt Protein Name    C-C motif chemokine 22
 UniProt Synonym Protein Names   
CC chemokine STCP-1; MDC(1-69); Macrophage-derived chemokine; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1
 Protein Family    C-C motif chemokine
 UniProt Gene Name    CCL22 [Similar Products]
 UniProt Synonym Gene Names    MDC; SCYA22 [Similar Products]
 UniProt Entry Name    CCL22_HUMAN
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 NCBI Summary for CCL22    This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]
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 UniProt Comments for CCL22    CCL22: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Chemokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: extracellular region

Molecular Function: CCR chemokine receptor binding

Biological Process: cell-cell signaling; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity; response to virus; signal transduction
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 Research Articles on CCL22    1. Our results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CCL22 cdna cloneDiseases associated with CCL22 cdna clone
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >151 publications with CCL22 and Inflammation
 Hypersensitivity Antibodies  >132 publications with CCL22 and Hypersensitivity
 Skin Diseases Antibodies  >110 publications with CCL22 and Skin Diseases
 Lung Diseases Antibodies  >89 publications with CCL22 and Lung Diseases
 Necrosis Antibodies  >63 publications with CCL22 and Necrosis
 Dermatitis, Atopic Antibodies  >61 publications with CCL22 and Dermatitis, Atopic
 Nervous System Diseases Antibodies  >36 publications with CCL22 and Nervous System Diseases
 Pneumonia Antibodies  >13 publications with CCL22 and Pneumonia
 Skin Neoplasms Antibodies  >12 publications with CCL22 and Skin Neoplasms
 Fibrosis Antibodies  >11 publications with CCL22 and Fibrosis
Organs/Tissues associated with CCL22 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >432 publications with CCL22 and Blood
 Thymus Antibodies  >123 publications with CCL22 and Thymus
 Skin Antibodies  >110 publications with CCL22 and Skin
 Lung Antibodies  >88 publications with CCL22 and Lung
 Bone Antibodies  >37 publications with CCL22 and Bone
 Kidney Antibodies  >11 publications with CCL22 and Kidney
 Eye Antibodies  >9 publications with CCL22 and Eye
 Mouth Antibodies  >3 publications with CCL22 and Mouth
 Pharynx Antibodies  >3 publications with CCL22 and Pharynx
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