Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow cDNA Clone rightarrow CD247  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Notch 1 (NOTCH1) Antibody
 • A kinase (PRKA) anchor protein 12 (AKAP12) ELISA Kit
 • FBXO32 Antibody
 • CXCL1 ELISA Kit
 • EDG1 Antibody
 • WAP four-disulfide core domain protein 12 (WFDC12) Recombinant Protein
 • Collagen Type IV (Col IV) ELISA Kit
 • RIPK1 Antibody
 • ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) (UBE... ELISA Kit
 • Creatinine N Antibody
 • Antithrombin Receptor (ATR) ELISA Kit
 • Piezo-type mechanosensitive ion channel component 1 (Piezo1)... Recombinant Protein
 • ENPP1 - PC1 Peptide
 • CRFR1 - CRHR1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CD247 cdna clone

Scan QR to view Datasheet Catalog #    MBS1278153 CD247 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD247, cDNA Clone

 Also Known As   

CD247 cDNA Clone

 Product Gene Name   

CD247 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Application Notes    The full plasmid sequence is not standardly provided for this product. Sequencing report may be available for an additional fee with cDNA product purchase, please inquire.
 Sequence    atgaagtgga aggcgctttt caccgcggcc atcctgcagg cacagttgcc gattacagag gcacagagct ttggcctgct ggatcccaaa ctctgctacc tgctggatgg aatcctcttc atctatggtg tcattctcac tgccttgttc ctgagagtga agttcagcag gagcgcagac gcccccgcgt accagcaggg ccagaaccag ctctataacg agctcaatct aggacgaaga gaggagtacg atgttttgga caagagacgt ggccgggacc ctgagatggg gggaaagccg cagagaagga agaaccctca ggaaggcctg tacaatgaac tgcagaaaga taagatggcg gaggcctaca gtgagattgg gatgaaaggc gagcgccgga ggggcaaggg gcacgatggc ctttaccagg gtctcagtac agccaccaag gacacctacg acgcccttca catgcaggcc ctgccccctc gctaa
 OMIM    186780
Section Bar
Section Bar
Section Bar
 Vector    Please Inquire
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CD247 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD247. It may not necessarily be applicable to this product.
 NCBI GI #    19344013
 NCBI GeneID    919
 NCBI Accession #    BC025703 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q5VX13; Q8TAX4; B1AK49 [Other Products]
 UniProt Related Accession #    P20963; A46461 [Other Products]
 Molecular Weight    – Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens CD247 molecule, mRNA
 NCBI Official Synonym Full Names    CD247 molecule
 NCBI Official Symbol    CD247 [Similar Products]
 NCBI Official Synonym Symbols   
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
[Similar Products]
 NCBI Protein Information    T-cell surface glycoprotein CD3 zeta chain
 UniProt Protein Name    T-cell surface glycoprotein CD3 zeta chain
 UniProt Synonym Protein Names   
T-cell receptor T3 zeta chain; CD_antigen: CD247
 Protein Family    T-cell surface glycoprotein
 UniProt Gene Name    CD247 [Similar Products]
 UniProt Synonym Gene Names    CD3Z; T3Z; TCRZ [Similar Products]
 UniProt Entry Name    CD3Z_HUMAN
Section Bar
 NCBI Summary for CD247    The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CD247    CD3Z: a T cell surface glycoprotein that is a component of the T cell antigen receptor. Plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the CD3-epsilon results in impaired immune response. Two alternatively spliced isoforms have been described.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: cytoplasm; plasma membrane; T cell receptor complex

Molecular Function: identical protein binding; protein binding

Biological Process: regulation of defense response to virus by virus; regulation of immune response; T cell costimulation; T cell receptor signaling pathway

Disease: Immunodeficiency 25
Table BarTOPTable Bar
 Research Articles on CD247    1. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 activation in oral cancer.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with CD247 cdna cloneDiseases associated with CD247 cdna clone
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream TCR Signaling Pathway antibodies  Downstream TCR Signaling Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >6 publications with CD247 and Immune System Diseases
 Skin Diseases Antibodies  >6 publications with CD247 and Skin Diseases
 Autoimmune Diseases Antibodies  >5 publications with CD247 and Autoimmune Diseases
 Neoplasms Antibodies  >4 publications with CD247 and Neoplasms
 Scleroderma, Systemic Antibodies  >4 publications with CD247 and Scleroderma, Systemic
 Inflammation Antibodies  >2 publications with CD247 and Inflammation
 Lung Diseases Antibodies  >1 publications with CD247 and Lung Diseases
 Breast Neoplasms Antibodies  >1 publications with CD247 and Breast Neoplasms
 Carcinoma Antibodies  >1 publications with CD247 and Carcinoma
 Hypertension Antibodies  >1 publications with CD247 and Hypertension
Organs/Tissues associated with CD247 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with CD247 and Blood
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions