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CD44 cdna clone

Scan QR to view Datasheet Catalog #    MBS1266130 CD44 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD44, cDNA Clone

★Popular Item★
 Also Known As   

CD44 cDNA Clone

 Product Gene Name   

CD44 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggacaagt tttggtggca cgcagcctgg ggactctgcc tcgtgccgct gagcctggcg cagatcgatt tgaatataac ctgccgcttt gcaggtgtat tccacgtgga gaaaaatggt cgctacagca tctctcggac ggaggccgct gacctctgca aggctttcaa tagcaccttg cccacaatgg cccagatgga gaaagctctg agcatcggat ttgagacctg caggtatggg ttcatagaag ggcatgtggt gattccccgg atccacccca actccatctg tgcagcaaac aacacagggg tgtacatcct cacatccaac acctcccagt atgacacata ttgcttcaat gcttcagctc cacctgaaga agattgtaca tcagtcacag acctgcccaa tgcctttgat ggaccaatta ccataactat tgttaaccgt gatggcaccc gctatgtcca gaaaggagaa tacagaacga atcctgaaga catctacccc agcaacccta ctgatgatga cgtgagcagc ggctcctcca gtgaaaggag cagcacttca ggaggttaca tcttttacac cttttctact gtacacccca tcccagacga agacagtccc tggatcaccg acagcacaga cagaatccct gctaccagta cgtcttcaaa taccatctca gcaggctggg agccaaatga agaaaatgaa gatgaaagag acagacacct cagtttttct ggatcaggca ttgatgatga tgaagatttt atctccagca ccatttcaac cacaccacgg gcttttgacc acacaaaaca gaaccaggac tggacccagt ggaacccaag ccattcaaat ccggaagtgc tacttcagac aaccacaagg atgactgatg tagacagaaa tggcaccact gcttatgaag gaaactggaa cccagaagca caccctcccc tcattcacca tgagcatcat gaggaagaag agaccccaca ttctacaagc acaatccagg caactcctag tagtacaacg gaagaaacag ctacccagaa ggaacagtgg tttggcaaca gatggcatga gggatatcgc caaacaccca gagaagactc ccattcgaca acagggacag ctgcagcctc agctcatacc agccatccaa tgcaaggaag gacaacacca agcccagagg acagttcctg gactgatttc ttcaacccaa tctcacaccc catgggacga ggtcatcaag caggaagaag gatggatatg gactccagtc atagtacaac gcttcagcct actgcaaatc caaacacagg tttggtggaa gatttggaca ggacaggacc tctttcaatg acaacgcagc agagtaattc tcagagcttc tctacatcac atgaaggctt ggaagaagat aaagaccatc caacaacttc tactctgaca tcaagcaata ggaatgatgt cacaggtgga agaagagacc caaatcattc tgaaggctca actactttac tggaaggtta tacctctcat tacccacaca cgaaggaaag caggaccttc atcccagtga cctcagctaa gactgggtcc tttggagtta ctgcagttac tgttggagat tccaactcta atgtcaatcg ttccttatca ggagaccaag acacattcca ccccagtggg gggtcccata ccactcatgg atctgaatca gatggacact cacatgggag tcaagaaggt ggagcaaaca caacctctgg tcctataagg acaccccaaa ttccagaatg gctgatcatc ttggcatccc tcttggcctt ggctttgatt cttgcagttt gcattgcagt caacagtcga agaaggtgtg ggcagaagaa aaagctagtg atcaacagtg gcaatggagc tgtggaggac agaaagccaa gtggactcaa cggagaggcc agcaagtctc aggaaatggt gcatttggtg aacaaggagt cgtcagaaac tccagaccag tttatgacag ctgatgagac aaggaacctg cagaatgtgg acatgaagat tggggtgtaa
 OMIM    107269
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CD44 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CD44. It may not necessarily be applicable to this product.
 NCBI GI #    13325117
 NCBI GeneID    960
 NCBI Accession #    BC004372 [Other Products]
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 UniProt Secondary Accession #    O95370; P22511; Q04858; Q13419; Q13957; Q13958; Q13959; A5YRN9; B6EAT9; D3DR12; D3DR13 [Other Products]
 UniProt Related Accession #    P16070 [Other Products]
 Molecular Weight    15,635 Da
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 NCBI Official Full Name    Homo sapiens CD44 molecule (Indian blood group), mRNA
 NCBI Official Synonym Full Names    CD44 molecule (Indian blood group)
 NCBI Official Symbol    CD44 [Similar Products]
 NCBI Official Synonym Symbols   
IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
[Similar Products]
 NCBI Protein Information    CD44 antigen
 UniProt Protein Name    CD44 antigen
 UniProt Synonym Protein Names   
CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44
 Protein Family    CD44 antigen
 UniProt Gene Name    CD44 [Similar Products]
 UniProt Synonym Gene Names    LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I [Similar Products]
 UniProt Entry Name    CD44_HUMAN
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 NCBI Summary for CD44    The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD44    CD44: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Interacts with PKN2. Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment. Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. 19 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cell surface; cytoplasm; focal adhesion; Golgi apparatus; plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; hyaluronic acid binding; protein binding

Biological Process: cartilage development; extracellular matrix disassembly; extracellular matrix organization and biogenesis; hyaluronan catabolic process; leukocyte migration; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of heterotypic cell-cell adhesion; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation

Disease: Blood Group, Indian System
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 Research Articles on CD44    1. we also demonstrated frequent co-overexpression and positive correlation of DARPP-32, SRp20 and CD44E expression levels in human gastric primary tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CD44 cdna cloneDiseases associated with CD44 cdna clone
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hyaluronan Metabolism Pathway antibodies  Hyaluronan Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4132 publications with CD44 and Neoplasms
 Carcinoma Antibodies  >1664 publications with CD44 and Carcinoma
 Skin Diseases Antibodies  >871 publications with CD44 and Skin Diseases
 Inflammation Antibodies  >725 publications with CD44 and Inflammation
 Breast Neoplasms Antibodies  >704 publications with CD44 and Breast Neoplasms
 Disease Models, Animal Antibodies  >569 publications with CD44 and Disease Models, Animal
 Necrosis Antibodies  >457 publications with CD44 and Necrosis
 Neoplasms, Experimental Antibodies  >430 publications with CD44 and Neoplasms, Experimental
 Lung Diseases Antibodies  >421 publications with CD44 and Lung Diseases
 Carcinoma, Squamous Cell Antibodies  >387 publications with CD44 and Carcinoma, Squamous Cell
Organs/Tissues associated with CD44 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3775 publications with CD44 and Blood
 Bone Antibodies  >1378 publications with CD44 and Bone
 Bone Marrow Antibodies  >1069 publications with CD44 and Bone Marrow
 Vascular Antibodies  >955 publications with CD44 and Vascular
 Lymph Node Antibodies  >911 publications with CD44 and Lymph Node
 Lung Antibodies  >683 publications with CD44 and Lung
 Liver Antibodies  >604 publications with CD44 and Liver
 Spleen Antibodies  >560 publications with CD44 and Spleen
 Skin Antibodies  >519 publications with CD44 and Skin
 Embryonic Tissue Antibodies  >491 publications with CD44 and Embryonic Tissue
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