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CDK5R1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1273267 CDK5R1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CDK5R1, cDNA Clone

★Popular Item★
 Also Known As   

CDK5R1 cDNA Clone

 Product Gene Name   

CDK5R1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgggcacgg tgctgtccct gtctcccagc taccggaagg ccacgctgtt tgaggatggc gcggccaccg tgggccacta tacggccgta cagaacagca agaacgccaa ggacaagaac ctgaagcgcc actccatcat ctccgtgctg ccttggaaga gaatcgtggc cgtgtcggcc aagaagaaga actccaagaa ggtgcagccc aacagcagct accagaacaa catcacgcac ctcaacaatg agaacctgaa gaagtcgctg tcatgcgcca acctgtccac attcgcccag cccccaccgg cccagccgcc tgcacccccg gccagccagc tctcgggttc ccagaccggg ggctcctcct cagtcaagaa agcccctcac cctgccgtca cctccgcagg gacgcccaaa cgggtcatcg tccaggcgtc caccagtgag ctgcttcgct gcctgggtga gtttctctgc cgccggtgct accgcctgaa gcacctgtcc cccacggacc ccgtgctctg gctgcgcagc gtggaccgct cgctgcttct gcagggctgg caggaccagg gcttcatcac gccggccaac gtggtcttcc tctacatgct ctgcagggat gttatctcct ccaaggtggg ctcggatcac gagctccagg ccgtcctgct gacatgcctg tacctctcct actcctacat gggcaacgag atctcctacc cgctcaagcc cttcctggtg gagagctgca aggaggcctt ttgggaccgt tgcctctctg tcatcaacct catgagctca aagatgctgc agataaatgc cgacccacac tacttcacac aggtcttctc cgacctgaag aacgagagcg gccaggagga caagaagcgg ctcctcctag gcctggatcg gtga
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CDK5R1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CDK5R1. It may not necessarily be applicable to this product.
 NCBI GI #    20072247
 NCBI GeneID    8851
 NCBI Accession #    BC026347 [Other Products]
 Molecular Weight    34,059 Da
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 NCBI Official Full Name    Homo sapiens cyclin-dependent kinase 5, regulatory subunit 1 (p35), mRNA
 NCBI Official Synonym Full Names    cyclin dependent kinase 5 regulatory subunit 1
 NCBI Official Symbol    CDK5R1 [Similar Products]
 NCBI Official Synonym Symbols   
p23; p25; p35; CDK5R; NCK5A; CDK5P35; p35nck5a
[Similar Products]
 UniProt Protein Name    Cyclin-dependent kinase 5, regulatory subunit 1 (P35)
 UniProt Synonym Protein Names   
Cyclin-dependent kinase 5, regulatory subunit 1 (P35)
 Protein Family    Cyclin-dependent kinase 5 activator
 UniProt Gene Name    CDK5R1 [Similar Products]
 UniProt Entry Name    Q8TAM4_HUMAN
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 NCBI Summary for CDK5R1    The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer's disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease. [provided by RefSeq, Jul 2008]
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 Research Articles on CDK5R1    1. Under cell-free in vitro conditions, p35 is covalently modified by SUMO1. SUMO2 is conjugated to p35 in cells. The 2 major SUMO acceptor lysines in p35 are K246 and K290. Different degrees of oxidative stress resulted in differential p35 sumoylation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CDK5R1 cdna cloneDiseases associated with CDK5R1 cdna clone
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CRMPs In Sema3A Signaling Pathway antibodies  CRMPs In Sema3A Signaling Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with CDK5R1 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with CDK5R1 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with CDK5R1 and Neurobehavioral Manifestations
 Movement Disorders Antibodies  >2 publications with CDK5R1 and Movement Disorders
 Neoplasms Antibodies  >2 publications with CDK5R1 and Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with CDK5R1 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with CDK5R1 and Neoplasms, Experimental
 Drug Toxicity Antibodies  >1 publications with CDK5R1 and Drug Toxicity
 Inflammation Antibodies  >1 publications with CDK5R1 and Inflammation
Organs/Tissues associated with CDK5R1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with CDK5R1 and Brain
 Embryonic Tissue Antibodies  >1 publications with CDK5R1 and Embryonic Tissue
 Lung Antibodies  >1 publications with CDK5R1 and Lung
 Liver Antibodies  >1 publications with CDK5R1 and Liver
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