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CDK7 cdna clone

Scan QR to view Datasheet Catalog #    MBS1268000 CDK7 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CDK7, cDNA Clone

★Popular Item★
 Also Known As   

CDK7 cDNA Clone

 Product Gene Name   

CDK7 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctctgg acgtgaagtc tcgggcaaag cgttatgaga agctggactt ccttggggag ggacagtttg ccaccgttta caaggccaga gataagaaca ccaaccaaat tgtcgccatt aagaaaatca aacttggaca tagatcagaa gctaaagatg gtataaatag aaccgcctta agagagataa aattattaca ggagctaagt catccaaata taattggtct ccttgatgct tttggacata aatctaatat tagccttgtc tttgatttta tggaaactga tctagaggtt ataataaagg ataatagtct tgtgctgaca ccatcacaca tcaaagccta catgttgatg actcttcaag gattagaata tttacatcaa cattggatcc tacataggga tctgaaacca aacaacttgt tgctagatga aaatggagtt ctaaaactgg cagattttgg cctggccaaa tcttttggga gccccaatag agcttataca catcaggttg taaccaggtg gtatcgggcc cccgagttac tatttggagc taggatgtat ggtgtaggtg tggacatgtg ggctgttggc tgtatattag cagagttact tctaagggtt ccttttttgc caggagattc agaccttgat cagctaacaa gaatatttga aactttgggc acaccaactg aggaacagtg gccggacatg tgtagtcttc cagattatgt gacatttaag agtttccctg gaataccttt gcatcacatc ttcagtgcag caggagacga cttactagat ctcatacaag gcttattctt atttaatcca tgtgctcgaa ttacggccac acaggcactg aaaatgaagt atttcagtaa tcggccaggg ccaacacctg gatgtcagct gccaagacca aactgtccag tggaaacctt aaaggagcaa tcaaatccag ctttggcaat aaaaaggaaa agaacagagg ccttagaaca aggaggattg cccaagaaac taatttttta a
 OMIM    601955
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CDK7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CDK7. It may not necessarily be applicable to this product.
 NCBI GI #    34783068
 NCBI GeneID    1022
 NCBI Accession #    BC000834 [Other Products]
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 UniProt Secondary Accession #    Q9BS60; Q9UE19 [Other Products]
 UniProt Related Accession #    P50613 [Other Products]
 Molecular Weight    39,038 Da
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 NCBI Official Full Name    Homo sapiens cyclin-dependent kinase 7, mRNA
 NCBI Official Synonym Full Names    cyclin dependent kinase 7
 NCBI Official Symbol    CDK7 [Similar Products]
 NCBI Official Synonym Symbols   
CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15
[Similar Products]
 NCBI Protein Information    cyclin-dependent kinase 7
 UniProt Protein Name    Cyclin-dependent kinase 7
 UniProt Synonym Protein Names   
39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit
 Protein Family    Cyclin-dependent kinase
 UniProt Gene Name    CDK7 [Similar Products]
 UniProt Synonym Gene Names    CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15 [Similar Products]
 UniProt Entry Name    CDK7_HUMAN
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 NCBI Summary for CDK7    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CDK7    CDK7: a protein kinase of the CDK family. Forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). Activates the cyclin-associated kinases CDK1, -2, -4 and -6. An essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. Serves as a direct link between the regulation of transcription and the cell cycle. Phosphorylates and activates RNA polymerase II, allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Protein type: Kinase, protein; EC 2.7.11.22; Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.23; Protein kinase, CMGC; Nuclear receptor co-regulator; CMGC group; CDK family; CDK7 subfamily; CDK/CDK7 subfamily

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: cytoplasm; holo TFIIH complex; mitochondrion; nucleoplasm; nucleus

Molecular Function: DNA-dependent ATPase activity; kinase activity; protein binding; protein C-terminus binding; protein kinase activity; protein serine/threonine kinase activity; RNA polymerase subunit kinase activity

Biological Process: cell cycle arrest; cell proliferation; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; mRNA capping; nucleotide-excision repair, preincision complex assembly; positive regulation of transcription from RNA polymerase II promoter; regulation of cyclin-dependent protein kinase activity; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair
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 Research Articles on CDK7    1. Cdk7 broadly influences transcription and capping.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CDK7 cdna cloneDiseases associated with CDK7 cdna clone
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cyclin A/B1 Associated Events During G2/M Transition Pathway antibodies  Cyclin A/B1 Associated Events During G2/M Transition Pathway Diagram
 Cyclin A:Cdk2-associated Events At S Phase Entry Pathway antibodies  Cyclin A:Cdk2-associated Events At S Phase Entry Pathway Diagram
 Cyclin D Associated Events In G1 Pathway antibodies  Cyclin D Associated Events In G1 Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >96 publications with CDK7 and Neoplasms
 Breast Neoplasms Antibodies  >15 publications with CDK7 and Breast Neoplasms
 Liver Neoplasms Antibodies  >12 publications with CDK7 and Liver Neoplasms
 Nervous System Diseases Antibodies  >11 publications with CDK7 and Nervous System Diseases
 Liver Diseases Antibodies  >10 publications with CDK7 and Liver Diseases
 Lung Neoplasms Antibodies  >8 publications with CDK7 and Lung Neoplasms
 Brain Diseases Antibodies  >8 publications with CDK7 and Brain Diseases
 Drug Toxicity Antibodies  >8 publications with CDK7 and Drug Toxicity
 Carcinoma, Hepatocellular Antibodies  >8 publications with CDK7 and Carcinoma, Hepatocellular
 Precancerous Conditions Antibodies  >6 publications with CDK7 and Precancerous Conditions
Organs/Tissues associated with CDK7 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >19 publications with CDK7 and Liver
 Blood Antibodies  >17 publications with CDK7 and Blood
 Muscle Antibodies  >13 publications with CDK7 and Muscle
 Heart Antibodies  >10 publications with CDK7 and Heart
 Brain Antibodies  >10 publications with CDK7 and Brain
 Lung Antibodies  >9 publications with CDK7 and Lung
 Eye Antibodies  >6 publications with CDK7 and Eye
 Prostate Antibodies  >6 publications with CDK7 and Prostate
 Embryonic Tissue Antibodies  >4 publications with CDK7 and Embryonic Tissue
 Skin Antibodies  >4 publications with CDK7 and Skin
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