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CPT1A cdna clone

Scan QR to view Datasheet Catalog #    MBS1277321 CPT1A cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CPT1A, cDNA Clone

★Popular Item★
 Also Known As   

CPT1A cDNA Clone

 Product Gene Name   

CPT1A cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcagaag ctcaccaagc tgtggccttt cagttcacgg tcactccgga cgggattgac ctgcggctga gccatgaagc tcttagacaa atctatctct ctggacttca ttcctggaaa aagaagttca tcagattcaa gaacggcatc atcactggcg tgtacccggc aagcccctcc agttggctta tcgtggtggt gggcgtgatg acaacgatgt acgccaagat cgacccctcg ttaggaataa ttgcaaaaat caatcggact ctggaaacgg ccaactgcat gtccagccag acgaagaacg tggtcagcgg cgtgctgttt ggcaccggcc tgtgggtggc cctcatcgtc accatgcgct actccctgaa agtgctgctc tcctaccacg ggtggatgtt cactgagcac ggcaagatga gtcgtgccac caagatctgg atgggtatgg tcaagatctt ttcaggccga aaacccatgt tgtacagctt ccagacatcg ctgcctcgcc tgccggtccc ggctgtcaaa gacactgtga acaggtatct acagtcggtg aggcctctta tgaaggaaga agacttcaaa cggatgacag cacttgctca agattttgct gtcggtcttg gaccaagatt acagtggtat ttgaagttaa aatcctggtg ggctacaaat tacgtgagcg actggtggga ggagtacatc tacctccgag gacgagggcc gctcatggtg aacagcaact attatgccat ggatctgctg tatatccttc caactcacat tcaggcagca agagccggca acgccatcca tgccatcctg ctttacaggc gcaaactgga ccgggaggaa atcaaaccaa ttcgtctttt gggatccacg attccactct gctccgctca gtgggagcgg atgtttaata cttcccggat cccaggagag gagacagaca ccatccagca catgagagac agcaagcaca tcgtcgtgta ccatcgagga cgctacttca aggtctggct ctaccatgat gggcggctgc tgaagccccg ggagatggag cagcagatgc agaggatcct ggacaatacc tcggagcctc agcccgggga ggccaggctg gcagccctca ccgcaggaga cagagttccc tgggccaggt gtcgtcaggc ctattttgga cgtgggaaaa ataagcagtc tcttgatgct gtggagaaag cagcgttctt cgtgacgtta gatgaaactg aagaaggata cagaagtgaa gacccggata cgtcaatgga cagctacgcc aaatctctac tacacggccg atgttacgac aggtggtttg acaagtcgtt cacgtttgtt gtcttcaaaa acgggaagat gggcctcaac gctgaacact cctgggcaga tgcgccgatc gtggcccacc tttgggagta cgtcatgtcc attgacagcc tccagctggg ctatgcggag gatgggcact gcaaaggcga catcaatccg aacattccgt accccaccag gctgcagtgg gacatcccgg gggaatgtca agaggttata gagacctccc tgaacaccgc aaatcttctg gcaaacgacg tggatttcca ttccttccca ttcgtagcct ttggtaaagg aatcatcaag aaatgtcgca cgagcccaga cgcctttgtg cagctggccc tccagctggc gcactacaag gacatgggca agttttgcct cacatacgag gcctccatga cccggctctt ccgagagggg aggacggaga ccgtgcgctc ctgcaccact gagtcatgcg acttcgtgcg ggccatggtg gacccggccc agacggtgga acagaggctg aagttgttca agttggcgtc tgagaagcat cagcatatgt atcgcctcgc catgaccggc tctgggatcg atcgtcacct cttctgcctt tacgtggtgt ctaaatatct cgctgtggag tcccctttcc ttaaggaagt tttatctgag ccttggagat tatcaacaag ccagacccct cagcagcaag tggagctgtt tgacttggag aataacccag agtacgtgtc cagcggaggg ggctttggac cggttgctga tgacggctat ggtgtgtcgt acatccttgt gggagagaac ctcatcaatt tccacatttc ttccaagttc tcttgccctg agacggggat tataagtcaa ggaccaagtt cagatacttg a
 OMIM    255120
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CPT1A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CPT1A. It may not necessarily be applicable to this product.
 NCBI GI #    12652864
 NCBI GeneID    1374
 NCBI Accession #    BC000185 [Other Products]
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 UniProt Secondary Accession #    Q8TCU0; Q9BWK0 [Other Products]
 UniProt Related Accession #    P50416 [Other Products]
 Molecular Weight    86,239 Da
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 NCBI Official Full Name    Homo sapiens carnitine palmitoyltransferase 1A (liver), mRNA
 NCBI Official Synonym Full Names    carnitine palmitoyltransferase 1A
 NCBI Official Symbol    CPT1A [Similar Products]
 NCBI Official Synonym Symbols   
CPT1; CPT1-L; L-CPT1
[Similar Products]
 NCBI Protein Information    carnitine O-palmitoyltransferase 1, liver isoform
 UniProt Protein Name    Carnitine O-palmitoyltransferase 1, liver isoform
 UniProt Synonym Protein Names   
Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
 Protein Family    Carnitine O-palmitoyltransferase
 UniProt Gene Name    CPT1A [Similar Products]
 UniProt Synonym Gene Names    CPT1; CPT1-L; CPT I; CPTI-L [Similar Products]
 UniProt Entry Name    CPT1A_HUMAN
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 NCBI Summary for CPT1A    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CPT1A    CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; Membrane protein, integral; Lipid Metabolism - fatty acid; EC 2.3.1.21; Mitochondrial; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: integral to mitochondrial outer membrane; membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: carnitine O-palmitoyltransferase activity

Biological Process: carnitine metabolic process; carnitine shuttle; circadian rhythm; epithelial cell differentiation; long-chain fatty acid metabolic process

Disease: Carnitine Palmitoyltransferase I Deficiency
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 Research Articles on CPT1A    1. Methylation at 2 CpG sites in CPT1A on chromosome 11 was significantly associated with MetS. Significant associations were replicated in both European and African ancestry participants.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CPT1A cdna cloneDiseases associated with CPT1A cdna clone
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway antibodies  Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >61 publications with CPT1A and Fatty Liver
 Liver Diseases Antibodies  >26 publications with CPT1A and Liver Diseases
 Insulin Resistance Antibodies  >21 publications with CPT1A and Insulin Resistance
 Inflammation Antibodies  >10 publications with CPT1A and Inflammation
 Atherosclerosis Antibodies  >6 publications with CPT1A and Atherosclerosis
 Liver Neoplasms Antibodies  >6 publications with CPT1A and Liver Neoplasms
 Diabetes Mellitus Antibodies  >6 publications with CPT1A and Diabetes Mellitus
 Weight Gain Antibodies  >5 publications with CPT1A and Weight Gain
 Carcinoma, Hepatocellular Antibodies  >5 publications with CPT1A and Carcinoma, Hepatocellular
 Hepatitis Antibodies  >5 publications with CPT1A and Hepatitis
Organs/Tissues associated with CPT1A cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >81 publications with CPT1A and Liver
 Blood Antibodies  >39 publications with CPT1A and Blood
 Muscle Antibodies  >28 publications with CPT1A and Muscle
 Brain Antibodies  >11 publications with CPT1A and Brain
 Kidney Antibodies  >8 publications with CPT1A and Kidney
 Connective Tissue Antibodies  >4 publications with CPT1A and Connective Tissue
 Vascular Antibodies  >3 publications with CPT1A and Vascular
 Thyroid Antibodies  >3 publications with CPT1A and Thyroid
 Bone Antibodies  >3 publications with CPT1A and Bone
 Pancreas Antibodies  >3 publications with CPT1A and Pancreas
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