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CYB5A cdna clone

Scan QR to view Datasheet Catalog #    MBS1271589 CYB5A cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CYB5A, cDNA Clone

★Popular Item★
 Also Known As   

CYB5A cDNA Clone

 Product Gene Name   

CYB5A cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcagagc agtcggacga ggccgtgaag tactacaccc tagaggagat tcagaagcac aaccacagca agagcacctg gctgatcctg caccacaagg tgtacgattt gaccaaattt ctggaagagc atcctggtgg ggaagaagtt ttaagggaac aagctggagg tgacgctact gagaactttg aggatgtcgg gcactctaca gatgccaggg aaatgtccaa aacattcatc attggggagc tccatccaga tgacagacca aagttaaaca agcctccgga aactcttatc actactattg attctagttc cagttggtgg accaactggg tgatccctgc catctctgca gtggccgtcg ccttgatgta tcgcctatac atggcagagg actga
 OMIM    250790
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CYB5A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CYB5A. It may not necessarily be applicable to this product.
 NCBI GI #    15929505
 NCBI GeneID    1528
 NCBI Accession #    BC015182 [Other Products]
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 UniProt Secondary Accession #    Q6IB14; A8MV91; F8WEU4 [Other Products]
 UniProt Related Accession #    P00167 [Other Products]
 Molecular Weight    14,169 Da
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 NCBI Official Full Name    Homo sapiens cytochrome b5 type A (microsomal), mRNA
 NCBI Official Synonym Full Names    cytochrome b5 type A
 NCBI Official Symbol    CYB5A [Similar Products]
 NCBI Official Synonym Symbols   
CYB5; MCB5
[Similar Products]
 NCBI Protein Information    cytochrome b5
 UniProt Protein Name    Cytochrome b5
 UniProt Synonym Protein Names   
Microsomal cytochrome b5 type A; MCB5
 Protein Family    Cytochrome
 UniProt Gene Name    CYB5A [Similar Products]
 UniProt Synonym Gene Names    CYB5; MCB5 [Similar Products]
 UniProt Entry Name    CYB5_HUMAN
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 NCBI Summary for CYB5A    The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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 UniProt Comments for CYB5A    CYB5A: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A). A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. Belongs to the cytochrome b5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Oxidoreductase; Endoplasmic reticulum; Mitochondrial

Chromosomal Location of Human Ortholog: 18q23

Cellular Component: cytoplasm; intracellular membrane-bound organelle; membrane; mitochondrial outer membrane

Molecular Function: aldo-keto reductase activity; cytochrome-c oxidase activity; enzyme binding

Biological Process: L-ascorbic acid metabolic process

Disease: Methemoglobinemia Type Iv
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 Research Articles on CYB5A    1. We conclude that cytochrome b5 can influence the electronic conductivity of cytochrome P450c17 via allosteric, protein-protein interactions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CYB5A cdna cloneDiseases associated with CYB5A cdna clone
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Vitamin C (ascorbate) Metabolism Pathway antibodies  Vitamin C (ascorbate) Metabolism Pathway Diagram
 Cytochrome P450 Pathway antibodies  Cytochrome P450 Pathway Diagram
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with CYB5A and Breast Neoplasms
 Neoplasms Antibodies  >2 publications with CYB5A and Neoplasms
 Hyperplasia Antibodies  >2 publications with CYB5A and Hyperplasia
 Carcinoma Antibodies  >1 publications with CYB5A and Carcinoma
 Liver Cirrhosis Antibodies  >1 publications with CYB5A and Liver Cirrhosis
 Drug Toxicity Antibodies  >1 publications with CYB5A and Drug Toxicity
 Carcinoma, Hepatocellular Antibodies  >1 publications with CYB5A and Carcinoma, Hepatocellular
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with CYB5A and Prenatal Exposure Delayed Effects
 Liver Diseases Antibodies  >1 publications with CYB5A and Liver Diseases
Organs/Tissues associated with CYB5A cdna clone
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >5 publications with CYB5A and Testis
 Liver Antibodies  >5 publications with CYB5A and Liver
 Blood Antibodies  >2 publications with CYB5A and Blood
 Adrenal Gland Antibodies  >2 publications with CYB5A and Adrenal Gland
 Kidney Antibodies  >2 publications with CYB5A and Kidney
 Embryonic Tissue Antibodies  >2 publications with CYB5A and Embryonic Tissue
 Uterus Antibodies  >1 publications with CYB5A and Uterus
 Placenta Antibodies  >1 publications with CYB5A and Placenta
 Intestine Antibodies  >1 publications with CYB5A and Intestine
 Connective Tissue Antibodies  >1 publications with CYB5A and Connective Tissue
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