BC000051
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,448 Da
NCBI Official Full Name
Homo sapiens Fas apoptotic inhibitory molecule 2, mRNA
NCBI Official Synonym Full Names
Fas apoptotic inhibitory molecule 2
NCBI Official Synonym Symbols
LFG; LFG2; NGP35; NMP35; TMBIM2 [Similar Products]
NCBI Protein Information
protein lifeguard 2
UniProt Protein Name
Protein lifeguard 2
UniProt Synonym Protein Names
Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
UniProt Synonym Gene Names
UniProt Entry Name
LFG2_HUMAN
UniProt Comments for FAIM2
FAIM2: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. Belongs to the BI1 family. LFG subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: lipid raft
Biological Process: cerebellar granular layer development; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell layer development; cerebellum development; regulation of neuron apoptosis
Research Articles on FAIM2
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Pathways associated with FAIM2 cdna clone
Diseases associated with FAIM2 cdna clone
Organs/Tissues associated with FAIM2 cdna clone
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