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GABRA5 cdna clone

Scan QR to view Datasheet Catalog #    MBS1277184 GABRA5 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GABRA5, cDNA Clone

 Also Known As   

GABRA5 cDNA Clone

 Product Gene Name   

GABRA5 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggacaatg gaatgttctc tggttttatc atgatcaaaa acctccttct cttttgtatt tccatgaact tatccagtca ctttggcttt tcacagatgc caaccagttc agtgaaagat gagaccaatg acaacatcac gatatttacc aggatcttgg atgggctctt ggatggctac gacaacagac ttcggcccgg gctgggagag cgcatcactc aggtgaggac cgacatctac gtcaccagct tcggcccggt gtccgacacg gaaatggagt acaccataga cgtgtttttc cgacaaagct ggaaagatga aaggcttcgg tttaaggggc ccatgcagcg cctccctctc aacaacctcc ttgccagcaa gatctggacc ccagacacgt tcttccacaa cgggaagaag tccatcgctc acaacatgac cacgcccaac aagctgctgc ggctggagga cgacggcacc ctgctctaca ccatgcgctt gaccatctct gcagagtgcc ccatgcagct tgaggacttc ccgatggatg cgcacgcttg ccctctgaaa tttggcagct atgcgtaccc taattctgaa gtcgtctacg tctggaccaa cggctccacc aagtcggtgg tggtggcgga agatggctcc agactgaacc agtaccacct gatggggcag acggtgggca ctgagaacat cagcaccagc acaggcgaat acacaatcat gacagctcac ttccacctga aaaggaagat tggctacttt gtcatccaga cctaccttcc ctgcataatg accgtgatct tatcacaggt gtccttttgg ctgaaccggg aatcagtccc agccaggaca gtttttgggg tcaccacggt gctgaccatg acgaccctca gcatcagcgc caggaactct ctgcccaaag tggcctacgc caccgccatg gactggttca tagccgtgtg ctatgccttc gtcttctcgg cgctgataga gtttgccacg gtcaattact ttaccaagag aggctgggcc tgggatggca aaaaagcctt ggaagcagcc aagatcaaga aaaagcgtga agtcatacta aataagtcaa caaacgcttt tacaactggg aagatgtctc accccccaaa cattccgaag gaacagaccc cagcagggac gtcgaataca acctcagtct cagtaaaacc ctctgaagag aagacttctg aaagcaaaaa gacttacaac agtatcagca aaattgacaa aatgtcccga atcgtattcc cagtcttgtt cggcactttc aacttagttt actgggcaac gtatttgaat agggagccgg tgataaaagg agccgcctct ccaaaataa
 OMIM    137142
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GABRA5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for GABRA5. It may not necessarily be applicable to this product.
 NCBI GI #    15030265
 NCBI GeneID    2558
 NCBI Accession #    BC011403 [Other Products]
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 UniProt Secondary Accession #    Q14DC2; Q53XL6; Q9NYT3; Q9NYT4; Q9NYT5; A8K338 [Other Products]
 UniProt Related Accession #    P31644; AAB22608 [Other Products]
 Molecular Weight    52,146 Da
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 NCBI Official Full Name    Homo sapiens cDNA clone IMAGE:3868411, **** WARNING: chimeric clone ****
 NCBI Official Synonym Full Names    gamma-aminobutyric acid type A receptor alpha5 subunit
 NCBI Official Symbol    GABRA5 [Similar Products]
 NCBI Protein Information    gamma-aminobutyric acid receptor subunit alpha-5
 UniProt Protein Name    Gamma-aminobutyric acid receptor subunit alpha-5
 UniProt Synonym Protein Names   
GABA(A) receptor subunit alpha-5
 Protein Family    Gamma-aminobutyric acid receptor
 UniProt Gene Name    GABRA5 [Similar Products]
 UniProt Entry Name    GBRA5_HUMAN
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 NCBI Summary for GABRA5    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GABRA5    GABRA5: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: GABA-A receptor activity; receptor activity; transporter activity

Biological Process: positive regulation of defense response to virus by host; signal transduction; transport
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 Research Articles on GABRA5    1. Report benzodiazepine derivative as GABA-site inhibitor of extra-synaptic GABAA alpha5 receptors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GABRA5 cdna cloneDiseases associated with GABRA5 cdna clone
 Products by Pathway  Pathway Diagram
 GABA A Receptor Activation Pathway antibodies  GABA A Receptor Activation Pathway Diagram
 GABA Receptor Activation Pathway antibodies  GABA Receptor Activation Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ligand-gated Ion Channel Transport Pathway antibodies  Ligand-gated Ion Channel Transport Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >51 publications with GABRA5 and Nervous System Diseases
 Mental Disorders Antibodies  >40 publications with GABRA5 and Mental Disorders
 Congenital Abnormalities Antibodies  >27 publications with GABRA5 and Congenital Abnormalities
 Neurobehavioral Manifestations Antibodies  >24 publications with GABRA5 and Neurobehavioral Manifestations
 Epilepsy Antibodies  >21 publications with GABRA5 and Epilepsy
 Seizures Antibodies  >12 publications with GABRA5 and Seizures
 Autistic Disorder Antibodies  >11 publications with GABRA5 and Autistic Disorder
 Mood Disorders Antibodies  >11 publications with GABRA5 and Mood Disorders
 Memory Disorders Antibodies  >10 publications with GABRA5 and Memory Disorders
 Learning Disorders Antibodies  >9 publications with GABRA5 and Learning Disorders
Organs/Tissues associated with GABRA5 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >68 publications with GABRA5 and Brain
 Muscle Antibodies  >3 publications with GABRA5 and Muscle
 Testis Antibodies  >1 publications with GABRA5 and Testis
 Skin Antibodies  >1 publications with GABRA5 and Skin
 Kidney Antibodies  >1 publications with GABRA5 and Kidney
 Eye Antibodies  >1 publications with GABRA5 and Eye
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