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GABRA6 cdna clone

Scan QR to view Datasheet Catalog #    MBS1268176 GABRA6 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GABRA6, cDNA Clone

 Also Known As   

GABRA6 cDNA Clone

 Product Gene Name   

GABRA6 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    ATGGCGTCGT CTCTGCCCTG GCTGTGCATT ATTCTGTGGC TAGAAAATGC CCTAGGGAAA CTCGAAGTTG AAGGCAACTT CTACTCAGAA AACGTCAGTC GGATCCTGGA CAACTTGCTT GAAGGCTATG ACAATCGGCT GCGGCCGGGA TTTGGAGGTG CTGTCACTGA AGTCAAAACA GACATTTATG TGACCAGTTT TGGGCCCGTG TCAGATGTGG AGATGGAGTA TACGATGGAT GTTTTTTTCC GCCAGACCTG GACTGATGAG AGGTTGAAGT TTGGGGGGCC AACTGAGATT CTGAGTCTGA ATAATTTGAT GGTCAGTAAA ATCTGGACGC CTGACACCTT TTTCAGAAAT GGTAAAAAGT CCATTGCTCA CAACATGACA ACTCCTAATA AACTCTTCAG AATAATGCAG AATGGAACCA TTTTATACAC CATGAGGCTT ACCATCAATG CTGACTGTCC CATGAGGCTG GTTAACTTTC CTATGGATGG GCATGCTTGT CCACTCAAGT TTGGGAGCTA TGCTTATCCC AAAAGTGAAA TCATATATAC GTGGAAAAAA GGACCACTTT ACTCAGTAGA AGTCCCAGAA GAATCTTCAA GCCTTCTCCA GTATGATCTG ATTGGACAAA CAGTATCTAG TGAGACAATT AAATCTAACA CAGGTGAATA CGTTATAATG ACAGTTTACT TCCACTTGCA AAGGAAGATG GGCTACTTCA TGATACAGAT ATACACTCCT TGCATTATGA CAGTCATTCT TTCCCAGGTG TCTTTCTGGA TTAATAAGGA GTCCGTCCCA GCAAGAACTG TTTTTGGGAT CACCACTGTT TTAACTATGA CCACTTTGAG CATCAGTGCC CGGCACTCTT TGCCAAAAGT GTCATATGCC ACTGCCATGG ATTGGTTCAT AGCTGTTTGC TTTGCATTCG TCTTCTCTGC TCTTATCGAG TTCGCAGCTG TCAACTACTT TACCAATCTT CAGACACAGA AGGCCAAAAG GAAGGCACAG TTTGCAGCCC CACCCACAGT GACAATATCA AAAGCTACTG AACCTTTGGA AGCTGAGATT GTTTTGCATC CTGACTCCAA ATATCATCTG AAGAAAAGGA TCACTTCTCT GTCTTTGCCA ATAGTTTCAT CTTCCGAGGC CAATAAAGTG CTCACGAGAG CGCCCATCTT ACAATCAACA CCTGTCACAC CCCCACCACT CTCGCCAGCC TTTGGAGGCA CCAGTAAAAT AGACCAGTAT TCTCGAATTC TCTTCCCAGT TGCATTTGCA GGATTCAACC TTGTGTACTG GGTAGTTTAT CTTTCCAAAG ATACAATGGA AGTGAGTAGC AGTGTTGAAT AG
 OMIM    137143
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GABRA6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for GABRA6. It may not necessarily be applicable to this product.
 NCBI GI #    109731536
 NCBI GeneID    2559
 NCBI Accession #    BC096241 [Other Products]
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 UniProt Secondary Accession #    Q4VAV2; A8K096 [Other Products]
 UniProt Related Accession #    Q16445 [Other Products]
 Molecular Weight    51,024 Da
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 NCBI Official Full Name    Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 6, mRNA
 NCBI Official Synonym Full Names    gamma-aminobutyric acid type A receptor alpha6 subunit
 NCBI Official Symbol    GABRA6 [Similar Products]
 NCBI Protein Information    gamma-aminobutyric acid receptor subunit alpha-6
 UniProt Protein Name    Gamma-aminobutyric acid receptor subunit alpha-6
 UniProt Synonym Protein Names   
GABA(A) receptor subunit alpha-6
 Protein Family    Gamma-aminobutyric acid receptor
 UniProt Gene Name    GABRA6 [Similar Products]
 UniProt Entry Name    GBRA6_HUMAN
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 NCBI Summary for GABRA6    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GABRA6    GABRA6: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Channel, chloride; Membrane protein, integral; Transporter, ion channel

Chromosomal Location of Human Ortholog: 5q34

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: benzodiazepine receptor activity; GABA-A receptor activity

Biological Process: signal transduction; transport
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 Research Articles on GABRA6    1. TMEM132D, COMT and GABRA6 gene polymorphisms may influence susceptibility to panic disorder(PD) and major depressive disorder(MDD)in Japanese adults; these variants may increase vulnerability to PD by modulating oligodendrocytes and GABA and dopaminergic functions in related brain regions, altering neuronal processing of anxiety-related emotional signals
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GABRA6 cdna cloneDiseases associated with GABRA6 cdna clone
 Products by Pathway  Pathway Diagram
 GABA A Receptor Activation Pathway antibodies  GABA A Receptor Activation Pathway Diagram
 GABA Receptor Activation Pathway antibodies  GABA Receptor Activation Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ligand-gated Ion Channel Transport Pathway antibodies  Ligand-gated Ion Channel Transport Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >13 publications with GABRA6 and Nervous System Diseases
 Brain Diseases Antibodies  >12 publications with GABRA6 and Brain Diseases
 Central Nervous System Diseases Antibodies  >9 publications with GABRA6 and Central Nervous System Diseases
 Epilepsy Antibodies  >7 publications with GABRA6 and Epilepsy
 Anxiety Disorders Antibodies  >6 publications with GABRA6 and Anxiety Disorders
 Seizures Antibodies  >6 publications with GABRA6 and Seizures
 Schizophrenia Antibodies  >4 publications with GABRA6 and Schizophrenia
 Ataxia Antibodies  >3 publications with GABRA6 and Ataxia
 Pain Antibodies  >2 publications with GABRA6 and Pain
 Unconsciousness Antibodies  >1 publications with GABRA6 and Unconsciousness
Organs/Tissues associated with GABRA6 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >43 publications with GABRA6 and Brain
 Muscle Antibodies  >1 publications with GABRA6 and Muscle
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