BC036094
[Other Products]
UniProt Related Accession #
Molecular Weight
15,610 Da
NCBI Official Full Name
Homo sapiens G antigen 1, mRNA
NCBI Official Synonym Full Names
G antigen 1
NCBI Protein Information
G antigen 1
UniProt Protein Name
G antigen 1
UniProt Synonym Protein Names
Antigen MZ2-F; Cancer/testis antigen 4.1; CT4.1
UniProt Synonym Gene Names
UniProt Entry Name
GAGE1_HUMAN
NCBI Summary for GAGE1
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
UniProt Comments for GAGE1
GAGE1: Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Completely silent in normal adult tissues, except testis. Belongs to the GAGE family.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp11.23
Molecular Function: protein binding
Biological Process: cellular defense response
Research Articles on GAGE1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with GAGE1 cdna clone
Organs/Tissues associated with GAGE1 cdna clone
|