Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow cDNA Clone rightarrow GNAT2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Cluster of Differentiation 28 (CD28) ELISA Kit
 • Cancer Antigen 242 (CA242) Antigen
 • Glycocalicin (GC) ELISA Kit
 • DR-70TM ELISA Kit
 • Avidin-peroxidase Secondary Antibody
 • Epidermal growth factor, EGF ELISA Kit
 • Interferon alpha, IFN-alpha ELISA Kit
 • DEDAF (RYBP) Antibody
 • Sperm protamine P1 (PRM1) Recombinant Protein
 • cortisol (COR) ELISA Kit
 • Desert hedgehog protein (DHH) Recombinant Protein
 • DNAJB6 cDNA Clone
 • ADCY1 ELISA Kit
 • Tryptophan 2,3-dioxygenase (Tdo2) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

GNAT2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1276807 GNAT2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GNAT2, cDNA Clone

 Also Known As   

GNAT2 cDNA Clone

 Product Gene Name   

GNAT2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgggaagtg gagccagtgc tgaggacaaa gaactggcca agaggtccaa ggagctagaa aagaagctgc aggaggatgc tgataaggaa gccaagactg tcaagctgct actgctgggt gctggggagt caggaaagag caccatcgtc aaacagatga agatcattca ccaggatggc tattcaccag aagaatgcct ggagttcaag gctatcatct atggaaatgt gctgcagtcc atcctggcta tcatccgggc catgaccaca ctgggcatcg attatgctga accaagctgt gcggatgacg ggcgacagct caacaacctg gctgactcca ttgaggaggg aaccatgcct cctgagctcg tggaggtcat taggaggttg tggaaggatg gtggggtgca agcctgcttc gagagagctg cagaatacca gcttaatgac tccgcatctt actacctgaa ccaattagaa cgaattacag accctgagta cctccctagt gagcaagatg tgctccgatc cagagtcaaa accacaggca tcattgaaac caagttttcc gtcaaagact tgaatttcag gatgtttgat gtgggagggc agagatccga gagaaagaag tggatccact gcttcgaggg agtcacctgc atcattttct gtgcagccct cagtgcctat gatatggtgc tggtggaaga tgacgaagtg aatcgtatgc atgagtcttt gcatctgttc aacagcatat gtaaccacaa attctttgcg gctacttcca ttgtcctctt tctcaacaag aaggacctct ttgaggaaaa aatcaagaaa gtccatctca gcatttgttt tccagagtat gatggtaaca actcctatga tgatgcgggg aattacataa agagccagtt ccttgacctc aatatgcgaa aagatgtcaa agaaatctac agtcacatga cctgtgctac agatacacag aatgtcaaat ttgtgtttga tgcagttaca gatattatca tcaaagaaaa cctcaaggac tgcggcctct tctaa
 OMIM    139340
Section Bar
Section Bar
Section Bar
 Vector    pUC
 Clone Sequence Report    Provided with product shipment
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GNAT2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GNAT2. It may not necessarily be applicable to this product.
 NCBI GI #    12652948
 NCBI GeneID    2780
 NCBI Accession #    BC000233 [Other Products]
Section Bar
 UniProt Related Accession #    P19087 [Other Products]
 Molecular Weight    40,176 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2, mRNA
 NCBI Official Synonym Full Names    G protein subunit alpha transducin 2
 NCBI Official Symbol    GNAT2 [Similar Products]
 NCBI Official Synonym Symbols   
ACHM4; GNATC
[Similar Products]
 NCBI Protein Information    guanine nucleotide-binding protein G(t) subunit alpha-2
 UniProt Protein Name    Guanine nucleotide-binding protein G(t) subunit alpha-2
 UniProt Synonym Protein Names   
Transducin alpha-2 chain
 UniProt Gene Name    GNAT2 [Similar Products]
 UniProt Synonym Gene Names    GNATC [Similar Products]
 UniProt Entry Name    GNAT2_HUMAN
Section Bar
 NCBI Summary for GNAT2    Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for GNAT2    G-alpha t2: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4). Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Protein type: G protein, heterotrimeric alpha G((i/o/t/z)); G protein, heterotrimeric; G protein

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: heterotrimeric G-protein complex; photoreceptor inner segment; photoreceptor outer segment; plasma membrane

Molecular Function: G-protein beta/gamma-subunit binding; G-protein-coupled receptor binding; GTP binding; GTPase activity; signal transducer activity

Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; detection of light stimulus involved in visual perception; G-protein signaling, coupled to cAMP nucleotide second messenger; protein folding; Wnt receptor signaling pathway, calcium modulating pathway

Disease: Achromatopsia 4
Table BarTOPTable Bar
 Research Articles on GNAT2    1. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (p.T383fsX and p.T296YfsX9) and three in CNGA3 (p.R283Q, p.R427C and p.L527R).
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with GNAT2 cdna cloneDiseases associated with GNAT2 cdna clone
 Products by Pathway  Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G-protein Activation Pathway antibodies  G-protein Activation Pathway Diagram
 G-protein Mediated Events Pathway antibodies  G-protein Mediated Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Opioid Signalling Pathway antibodies  Opioid Signalling Pathway Diagram
 PLC Beta Mediated Events Pathway antibodies  PLC Beta Mediated Events Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Eye Diseases Antibodies  >39 publications with GNAT2 and Eye Diseases
 Nervous System Diseases Antibodies  >23 publications with GNAT2 and Nervous System Diseases
 Color Vision Defects Antibodies  >19 publications with GNAT2 and Color Vision Defects
 Neoplasms Antibodies  >2 publications with GNAT2 and Neoplasms
 Kidney Diseases Antibodies  >1 publications with GNAT2 and Kidney Diseases
 Congenital Abnormalities Antibodies  >1 publications with GNAT2 and Congenital Abnormalities
 Abnormalities, Drug-Induced Antibodies  >1 publications with GNAT2 and Abnormalities, Drug-Induced
 Atrophy Antibodies  >1 publications with GNAT2 and Atrophy
 Drug Toxicity Antibodies  >1 publications with GNAT2 and Drug Toxicity
 Brain Diseases Antibodies  >1 publications with GNAT2 and Brain Diseases
Organs/Tissues associated with GNAT2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >51 publications with GNAT2 and Eye
 Kidney Antibodies  >1 publications with GNAT2 and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions