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HERPUD1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1269048 HERPUD1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HERPUD1, cDNA Clone

★Popular Item★
 Also Known As   

HERPUD1 cDNA Clone

 Product Gene Name   

HERPUD1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggagtccg agaccgaacc cgagcccgtc acgctcctgg tgaagagccc caaccagcgc caccgcgact tggagctgag tggcgaccgc ggctggagtg tgggccacct caaggcccac ctgagccgcg tctaccccga gcgtccgcgt ccagaggacc agaggttaat ttattctggg aagctgttgt tggatcacca atgtctcagg gacttgcttc caaaggaaaa acggcatgtt ttgcatctgg tgtgcaatgt gaagagtcct tcaaaaatgc cagaaatcaa cgccaaggtg gctgaatcca cagaggagcc tgctggttct aatcggggac agtatcctga ggattcctca agtgatggtt taaggcaaag ggaagttctt cggaaccttt cttcccctgg atgggaaaac atctcaaggc atcacgttgg gtggtttcca tttagaccga ggccggttca gaacttccca aatgatggtc ctcctcctga cgttgtaaat caggacccca acaataactt acaggaaggc actgatcctg aaactgaaga ccccaaccac ctccctccag acagggatgt actagatggc gagcagacca gcccctcctt tatgagcaca gcatggcttg tcttcaagac tttctttgcc tctcttcttc cagaaggccc cccagccatc gcaaactga
 OMIM    608070
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HERPUD1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for HERPUD1. It may not necessarily be applicable to this product.
 NCBI GI #    16507801
 NCBI GeneID    9709
 NCBI Accession #    BC009739 [Other Products]
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 UniProt Secondary Accession #    O60644; Q6IAN8; Q96D92; E9PGD1 [Other Products]
 UniProt Related Accession #    Q15011 [Other Products]
 Molecular Weight    40,851 Da
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 NCBI Official Full Name    Homo sapiens homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, mRNA
 NCBI Official Synonym Full Names    homocysteine inducible ER protein with ubiquitin like domain 1
 NCBI Official Symbol    HERPUD1 [Similar Products]
 NCBI Official Synonym Symbols   
SUP; HERP; Mif1
[Similar Products]
 NCBI Protein Information    homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
 UniProt Protein Name    Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
 UniProt Synonym Protein Names   
Methyl methanesulfonate (MMF)-inducible fragment protein 1
 Protein Family    Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
 UniProt Gene Name    HERPUD1 [Similar Products]
 UniProt Synonym Gene Names    HERP; KIAA0025; MIF1 [Similar Products]
 UniProt Entry Name    HERP1_HUMAN
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 NCBI Summary for HERPUD1    The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
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 UniProt Comments for HERPUD1    HERPUD1: Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane

Molecular Function: protein binding

Biological Process: endoplasmic reticulum calcium ion homeostasis; response to unfolded protein; retrograde protein transport, ER to cytosol
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 Research Articles on HERPUD1    1. The results indicate that Nrf1 is a transcriptional activator of Herpud1 expression during ER stress, and they suggest Nrf1 is a key player in the regulation of the ER stress response in cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HERPUD1 cdna cloneDiseases associated with HERPUD1 cdna clone
 Products by Pathway  Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 HRD1/SEL1 ERAD Complex Pathway antibodies  HRD1/SEL1 ERAD Complex Pathway Diagram
 HRD1/SEL1 ERAD Complex Pathway antibodies  HRD1/SEL1 ERAD Complex Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 PERK Regulated Gene Expression Pathway antibodies  PERK Regulated Gene Expression Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Unfolded Protein Response Pathway antibodies  Unfolded Protein Response Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with HERPUD1 and Neoplasms
 Nervous System Diseases Antibodies  >5 publications with HERPUD1 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with HERPUD1 and Brain Diseases
 Inflammation Antibodies  >4 publications with HERPUD1 and Inflammation
 Drug Toxicity Antibodies  >3 publications with HERPUD1 and Drug Toxicity
 Kidney Diseases Antibodies  >3 publications with HERPUD1 and Kidney Diseases
 Disease Models, Animal Antibodies  >2 publications with HERPUD1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >2 publications with HERPUD1 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >2 publications with HERPUD1 and Neoplasm Metastasis
 Prostatic Neoplasms Antibodies  >2 publications with HERPUD1 and Prostatic Neoplasms
Organs/Tissues associated with HERPUD1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with HERPUD1 and Blood
 Kidney Antibodies  >4 publications with HERPUD1 and Kidney
 Brain Antibodies  >4 publications with HERPUD1 and Brain
 Vascular Antibodies  >3 publications with HERPUD1 and Vascular
 Muscle Antibodies  >3 publications with HERPUD1 and Muscle
 Lung Antibodies  >3 publications with HERPUD1 and Lung
 Embryonic Tissue Antibodies  >2 publications with HERPUD1 and Embryonic Tissue
 Prostate Antibodies  >2 publications with HERPUD1 and Prostate
 Nerve Antibodies  >2 publications with HERPUD1 and Nerve
 Heart Antibodies  >1 publications with HERPUD1 and Heart
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