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IARS2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1272669 IARS2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IARS2, cDNA Clone

 Also Known As   

IARS2 cDNA Clone

 Product Gene Name   

IARS2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgcctgaat caaagtatgc tgttgtgaaa tgttctaagt ctggagacct ctacgtactg gcggcagata aagtagcatc tgttgcttct actttggaaa caacatttga gactatttca acactttcag gtgtagattt ggaaaatggt acttgcagtc atccattaat tcctgataaa gcctctcctc ttttacctgc aaatcatgtg accatggcaa aaggaacggg attggttcac acagccccag ctcatggtat ggaagactac ggtgtagcgt ctcagcacaa cctgcccatg gattgtctag tggacgaaga tggagttttc acagatgttg caggtcctga acttcaaaac aaggctgtcc ttgaagaggg aactgatgtg gttataaaga tgcttcagac tgcaaagaat ttgttgaaag aggagaaatt ggtgcatagc tatccgtatg actggaggac caagaaacct gtggttattc gtgccagcaa gcagtggttt ataaacatca cggatattaa gactgcagcc aaggaattgt taaaaaaggt gaaatttatt cctggatcag cactgaatgg catggttgaa atgatggaca ggcggccata ttggtgtata tcaaggcaaa gagtttgggg tgttccaatt cctgtgtttc atcataagac caaggatgaa tacttgatca acagccaaac cactgagcat attgttaaac tagtggaaca acacggcagt gatatctggt ggactcttcc ccctgaacaa cttcttccaa aagaagtctt atctgaggtt ggtggccctg atgccttgga atatgtgcca ggtcaggata ttttggacat ctggtttgat agcggaactt catggtctta tgttcttcca ggtcctgacc aaagagcaga tttgtacttg gaaggaaaag accagctcgg gggttggttt cagtcatcct tattaacaag tgtggcagca aggaagagag caccttataa gacagtgatt gttcatggat ttacccttgg agaaaaggga gaaaagatgt ccaagtctct tgggaatgtc attcatcctg atgttgtcgt taatggagga caagatcaaa gcaaagagcc tccgtatggt gctgatgtcc ttcgctggtg ggtagctgat tccaatgtct tcaccgaagt tgcaattggc ccatccgtgc tcaatgctgc cagagatgat attagcaagc ttaggaatac acttcgcttt cttttgggaa atgtggctga tttcaaccca gaaacagatt ccatccctgt aaacgatatg tatgtcatag accagtacat gctacactta ctgcaggatt tggcaaacaa gattaccgaa ttatacaaac aatatgattt tggaaaagtt gttcggctgt tacggacgtt ttataccaga gagctctcta acttttattt cagtataatc aaagataggc tctattgtga aaaggaaaat gaccccaaac gacgctcttg tcagactgca ttagttgaaa ttttggatgt aatagttcgt tcttttgctc ccattcttcc tcacctggct gaagaggtgt tccagcacat accttatatt aaagagccca agagtgtttt ccgtactggg tggattagta ctagttctat ctggaaaaag cccgggttgg aagaagctgt ggagagtgcg tgtgcaatgc gagactcatt tcttggaagc atccctggca aaaatgcagc tgagtacaag gttatcactg tgatagaacc tggactgctt tttgagataa tagagatgct gcagtctgaa gagacttcca gcacctctca gttgaatgaa ttaatgatgg cttctgagtc aactttactg gctcaggaac cacgagagat gactgcagat gtaatcgagc ttaaagggaa attcctcatc aacttagaag gtggtgatat tcgtgaagag tcttcctata aagtaattgt catgccgact acgaaagaaa aatgcccccg ttgttggaag tatacagcgg agtcttcaga tacactgtgt cctcgatgtg cagaagttgt cagtggaaaa tag
 OMIM    612801
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 Vector    pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of IARS2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IARS2. It may not necessarily be applicable to this product.
 NCBI GI #    16307357
 NCBI GeneID    55699
 NCBI Accession #    BC010218 [Other Products]
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 UniProt Secondary Accession #    Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NW42; B2RPG8 [Other Products]
 UniProt Related Accession #    Q9NSE4 [Other Products]
 Molecular Weight    113,792 Da
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 NCBI Official Full Name    Homo sapiens isoleucyl-tRNA synthetase 2, mitochondrial, mRNA
 NCBI Official Synonym Full Names    isoleucyl-tRNA synthetase 2, mitochondrial
 NCBI Official Symbol    IARS2 [Similar Products]
 NCBI Official Synonym Symbols   
ILERS; CAGSSS
[Similar Products]
 NCBI Protein Information    isoleucine--tRNA ligase, mitochondrial
 UniProt Protein Name    Isoleucine--tRNA ligase, mitochondrial
 UniProt Synonym Protein Names   
Isoleucyl-tRNA synthetase; IleRS
 UniProt Gene Name    IARS2 [Similar Products]
 UniProt Synonym Gene Names    IleRS [Similar Products]
 UniProt Entry Name    SYIM_HUMAN
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 NCBI Summary for IARS2    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014]
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 UniProt Comments for IARS2    IARS2: Belongs to the class-I aminoacyl-tRNA synthetase family.

Protein type: Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; EC 6.1.1.5; Mitochondrial; Ligase

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: cytoplasm; cytosol; mitochondrial matrix; mitochondrion

Molecular Function: isoleucine-tRNA ligase activity

Biological Process: isoleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Disease: Cataracts, Growth Hormone Deficiency, Sensory Neuropathy, Sensorineural Hearing Loss, And Skeletal Dysplasia
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 Research Articles on IARS2    1. This study is the first report of clinical findings associated with IARS2 mutations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IARS2 cdna cloneDiseases associated with IARS2 cdna clone
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Mitochondrial TRNA Aminoacylation Pathway antibodies  Mitochondrial TRNA Aminoacylation Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >2 publications with IARS2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with IARS2 and Disease Models, Animal
Organs/Tissues associated with IARS2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with IARS2 and Blood
 Muscle Antibodies  >1 publications with IARS2 and Muscle
 Brain Antibodies  >1 publications with IARS2 and Brain
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