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IL29 cdna clone

Scan QR to view Datasheet Catalog #    MBS1273067 IL29 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL29, cDNA Clone

★Popular Item★
 Also Known As   

IL29 cDNA Clone

 Product Gene Name   

IL29 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggctgcag cttggaccgt ggtgctggtg actttggtgc taggcttggc cgtggcaggc cctgtcccca cttccaagcc caccacaact gggaagggct gccacattgg caggttcaaa tctctgtcac cacaggagct agcgagcttc aagaaggcca gggacgcctt ggaagagtca ctcaagctga aaaactggag ttgcagctct cctgtcttcc ccgggaattg ggacctgagg cttctccagg tgagggagcg ccctgtggcc ttggaggctg agctggccct gacgctgaag gtcctggagg ccgctgctgg cccagccctg gaggacgtcc tagaccagcc ccttcacacc ctgcaccaca tcctctccca gctccaggcc tgtatccagc ctcagcccac agcagggccc aggccccggg gccgcctcca ccactggctg caccggctcc aggaggcccc caaaaaggag tccgctggct gcctggaggc atctgtcacc ttcaacctct tccgcctcct cacgcgagac ctcaaatatg tggccgatgg ggacctgtgt ctgagaacgt caacccaccc tgagtccacc tga
 OMIM    607403
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of IL29 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IL29. It may not necessarily be applicable to this product.
 NCBI GI #    116496972
 NCBI GeneID    282618
 NCBI Accession #    BC126183 [Other Products]
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 UniProt Secondary Accession #    Q17R34; A0AV25 [Other Products]
 UniProt Related Accession #    Q8IU54 [Other Products]
 Molecular Weight    21,898 Da
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 NCBI Official Full Name    Homo sapiens interleukin 29 (interferon, lambda 1), mRNA
 NCBI Official Synonym Full Names    interferon lambda 1
 NCBI Official Symbol    IFNL1 [Similar Products]
 NCBI Official Synonym Symbols   
IL29; IL-29
[Similar Products]
 NCBI Protein Information    interferon lambda-1
 UniProt Protein Name    Interferon lambda-1
 UniProt Synonym Protein Names   
Cytokine Zcyto21; Interleukin-29; IL-29
 UniProt Gene Name    IFNL1 [Similar Products]
 UniProt Synonym Gene Names    IL29; ZCYTO21; IFN-lambda-1; IL-29 [Similar Products]
 UniProt Entry Name    IFNL1_HUMAN
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 NCBI Summary for IL29    This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL29    IL29: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.

Protein type: Cell cycle regulation; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.13

Cellular Component: extracellular region; extracellular space; interleukin-28 receptor complex

Molecular Function: interleukin-28 receptor binding; receptor binding

Biological Process: defense response to virus; innate immune response; negative regulation of cell proliferation; negative regulation of interleukin-13 production; negative regulation of interleukin-5 production; negative regulation of memory T cell differentiation; negative regulation of T cell differentiation; negative regulation of T-helper 2 type immune response; negative regulation of transcription, DNA-dependent; positive regulation of immune response; positive regulation of interferon-gamma production; positive regulation of JAK-STAT cascade; positive regulation of MHC class I biosynthetic process; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of STAT protein
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 Research Articles on IL29    1. IFN-lambda-1 and interferon-gamma levels in systemic sclerosis patients were significantly higher than those in healthy individuals.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IL29 cdna clone
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Type III Interferon Signaling Pathway antibodies  Type III Interferon Signaling Pathway Diagram
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