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IL8 cdna clone

Scan QR to view Datasheet Catalog #    MBS1275182 IL8 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL8, cDNA Clone

★Popular Item★
 Also Known As   

IL8 cDNA Clone

 Product Gene Name   

IL8 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgacttcca agctggccgt ggctctcttg gcagccttcc tgatttctgc agctctgtgt gaaggtgcag ttttgccaag gagtgctaaa gaacttagat gtcagtgcat aaagacatac tccaaacctt tccaccccaa atttatcaaa gaactgagag tgattgagag tggaccacac tgcgccaaca cagaaattat tgtaaagctt tctgatggaa gagagctctg tctggacccc aaggaaaact gggtgcagag ggttgtggag aagtttttga agagggctga gaattcataa
 OMIM    146930
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of IL8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IL8. It may not necessarily be applicable to this product.
 NCBI GI #    15488983
 NCBI GeneID    3576
 NCBI Accession #    BC013615 [Other Products]
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 UniProt Secondary Accession #    Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8; Q9UCR9; Q9UCS0; B2R4L8 [Other Products]
 UniProt Related Accession #    P10145 [Other Products]
 Molecular Weight    11,098 Da
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 NCBI Official Full Name    Homo sapiens interleukin 8, mRNA
 NCBI Official Synonym Full Names    C-X-C motif chemokine ligand 8
 NCBI Official Symbol    CXCL8 [Similar Products]
 NCBI Official Synonym Symbols   
IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
[Similar Products]
 NCBI Protein Information    interleukin-8
 UniProt Protein Name    Interleukin-8
 UniProt Synonym Protein Names   
C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1
 UniProt Gene Name    CXCL8 [Similar Products]
 UniProt Synonym Gene Names    IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF [Similar Products]
 UniProt Entry Name    IL8_HUMAN
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 NCBI Summary for IL8    The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL8    IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q13-q21

Cellular Component: extracellular region

Molecular Function: chemokine activity; interleukin-8 receptor binding; protein binding

Biological Process: angiogenesis; calcium-mediated signaling; cell cycle arrest; cell motility; chemotaxis; embryonic gut development; G-protein coupled receptor protein signaling pathway; immune response; induction of positive chemotaxis; inflammatory response; negative regulation of cell proliferation; negative regulation of G-protein coupled receptor protein signaling pathway; neutrophil activation; neutrophil chemotaxis; positive regulation of angiogenesis; receptor internalization; regulation of cell adhesion; regulation of retroviral genome replication; response to molecule of bacterial origin; signal transduction
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 Research Articles on IL8    1. Weight gain>5% was found in only 35.3% of the cases with NEC-III; combination of weight gain and IL-8 did not improve the diagnosis of NEC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IL8 cdna cloneDiseases associated with IL8 cdna clone
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >640 publications with IL8 and Inflammation
 Necrosis Antibodies  >381 publications with IL8 and Necrosis
 Hypersensitivity Antibodies  >65 publications with IL8 and Hypersensitivity
 Drug Toxicity Antibodies  >60 publications with IL8 and Drug Toxicity
 Pulmonary Disease, Chronic Obstructive Antibodies  >47 publications with IL8 and Pulmonary Disease, Chronic Obstructive
 Adenocarcinoma Antibodies  >45 publications with IL8 and Adenocarcinoma
 Pneumonia Antibodies  >34 publications with IL8 and Pneumonia
 Colorectal Neoplasms Antibodies  >30 publications with IL8 and Colorectal Neoplasms
 Breast Neoplasms Antibodies  >25 publications with IL8 and Breast Neoplasms
 Kidney Diseases Antibodies  >25 publications with IL8 and Kidney Diseases
Organs/Tissues associated with IL8 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >652 publications with IL8 and Blood
 Lung Antibodies  >227 publications with IL8 and Lung
 Vascular Antibodies  >194 publications with IL8 and Vascular
 Intestine Antibodies  >85 publications with IL8 and Intestine
 Skin Antibodies  >80 publications with IL8 and Skin
 Liver Antibodies  >68 publications with IL8 and Liver
 Heart Antibodies  >65 publications with IL8 and Heart
 Bone Antibodies  >57 publications with IL8 and Bone
 Muscle Antibodies  >56 publications with IL8 and Muscle
 Brain Antibodies  >46 publications with IL8 and Brain
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