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IRF5 cdna clone

Scan QR to view Datasheet Catalog #    MBS1267722 IRF5 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IRF5, cDNA Clone

★Popular Item★
 Also Known As   

IRF5 cDNA Clone

 Product Gene Name   

IRF5 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgaaccagt ccatcccagt ggctcccacc ccaccccgcc gcgtgcggct gaagccctgg ctggtggccc aggtgaacag ctgccagtac ccagggcttc aatgggtcaa cggggaaaag aaattattct gcatcccctg gaggcatgcc acaaggcatg gtcccagcca ggacggagat aacaccatct tcaaggcctg ggccaaggag acagggaaat acaccgaagg cgtggatgaa gccgatccgg ccaagtggaa ggccaacctg cgctgtgccc ttaacaagag ccgggacttc cgcctcatct acgacgggcc ccgggacatg ccacctcagc cctacaagat ctacgaggtc tgctccaatg gccctgctcc cacagactcc cagccccctg aggattactc ttttggtgca ggagaggagg aggaagaaga ggaagagctg cagaggatgt tgccaagcct gagcctcaca gaggatgtca agtggccgcc cactctgcag ccgcccactc tgcggccgcc tactctgcag ccgcccactc tgcagccgcc cgtggtgctg ggtccccctg ctccagaccc cagccccctg gctcctcccc ctggcaaccc tgctggcttc agggagcttc tctctgaggt cctggagcct gggcccctgc ctgccagcct gccccctgca ggcgaacagc tcctgccaga cctgctgatc agcccccaca tgctgcctct gaccgacctg gagatcaagt ttcagtaccg ggggcggcca ccccgggccc tcaccatcag caacccccat ggctgccggc tcttctacag ccagctggag gccacccagg agcaggtgga actcttcggc cccataagcc tggagcaagt gcgcttcccc agccctgagg acatccccag tgacaagcag cgcttctaca cgaaccagct gctggatgtc ctggaccgcg ggctcatcct ccagctacag ggccaggacc tttatgccat ccgcctgtgt cagtgcaagg tgttctggag cgggccttgt gcctcagccc atgactcatg ccccaacccc atccagcggg aggtcaagac caagcttttc agcctggagc attttctcaa tgagctcatc ctgttccaaa agggccagac caacacccca ccacccttcg agatcttctt ctgctttggg gaagaatggc ctgaccgcaa accccgagag aagaagctca ttactgtaca ggtggtgcct gtagcagctc gactgctgct ggagatgttc tcaggggagc tatcttggtc agctgatagt atccggctac agatctcaaa cccagacctc aaagaccgca tggtggagca attcaaggag ctccatcaca tctggcagtc ccagcagcgg ttgcagcctg tggcccaggc ccctcctgga gcaggccttg gtgttggcca ggggccctgg cctatgcacc cagctggcat gcaataa
 OMIM    180300
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of IRF5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IRF5. It may not necessarily be applicable to this product.
 NCBI GI #    34782796
 NCBI GeneID    3663
 NCBI Accession #    BC004139 [Other Products]
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 UniProt Secondary Accession #    Q1A7B4; Q64GA9; Q64GB1; Q64GB2; Q6RCM8; Q9BQF0; A4D1J8; A8DUA8; A8DUA9; E7EQ16; E7EW54 [Other Products]
 UniProt Related Accession #    Q13568 [Other Products]
 Molecular Weight    17,020 Da
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 NCBI Official Full Name    Homo sapiens interferon regulatory factor 5, mRNA
 NCBI Official Synonym Full Names    interferon regulatory factor 5
 NCBI Official Symbol    IRF5 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    interferon regulatory factor 5
 UniProt Protein Name    Interferon regulatory factor 5
 Protein Family    Interferon regulatory factor
 UniProt Gene Name    IRF5 [Similar Products]
 UniProt Synonym Gene Names    IRF-5 [Similar Products]
 UniProt Entry Name    IRF5_HUMAN
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 NCBI Summary for IRF5    This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]
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 UniProt Comments for IRF5    IRF5: Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. Homodimer, when phosphorylated. Belongs to the IRF family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: protein binding

Biological Process: positive regulation of apoptosis; positive regulation of interferon-alpha production; positive regulation of interferon-beta production; positive regulation of interleukin-12 production; positive regulation of transcription from RNA polymerase II promoter; response to muramyl dipeptide; response to peptidoglycan

Disease: Inflammatory Bowel Disease 14; Systemic Lupus Erythematosus, Susceptibility To, 10
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 Research Articles on IRF5    1. IRF5 and PADI4 significantly discriminated between RA patients and healthy controls in LDA.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IRF5 cdna cloneDiseases associated with IRF5 cdna clone
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Lupus Erythematosus, Systemic Antibodies  >125 publications with IRF5 and Lupus Erythematosus, Systemic
 Arthritis, Rheumatoid Antibodies  >50 publications with IRF5 and Arthritis, Rheumatoid
 Inflammation Antibodies  >39 publications with IRF5 and Inflammation
 Necrosis Antibodies  >20 publications with IRF5 and Necrosis
 Scleroderma, Systemic Antibodies  >19 publications with IRF5 and Scleroderma, Systemic
 Fibrosis Antibodies  >11 publications with IRF5 and Fibrosis
 Cardiovascular Diseases Antibodies  >8 publications with IRF5 and Cardiovascular Diseases
 Liver Diseases Antibodies  >8 publications with IRF5 and Liver Diseases
 Colitis, Ulcerative Antibodies  >7 publications with IRF5 and Colitis, Ulcerative
 Kidney Diseases Antibodies  >7 publications with IRF5 and Kidney Diseases
Organs/Tissues associated with IRF5 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >87 publications with IRF5 and Blood
 Connective Tissue Antibodies  >8 publications with IRF5 and Connective Tissue
 Spleen Antibodies  >7 publications with IRF5 and Spleen
 Bone Antibodies  >7 publications with IRF5 and Bone
 Mouth Antibodies  >6 publications with IRF5 and Mouth
 Kidney Antibodies  >6 publications with IRF5 and Kidney
 Bone Marrow Antibodies  >5 publications with IRF5 and Bone Marrow
 Brain Antibodies  >4 publications with IRF5 and Brain
 Lung Antibodies  >3 publications with IRF5 and Lung
 Prostate Antibodies  >1 publications with IRF5 and Prostate
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