BC045659
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,860 Da
NCBI Official Full Name
Homo sapiens potassium voltage-gated channel, Shal-related subfamily, member 1, mRNA
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily D member 1
NCBI Official Synonym Symbols
NCBI Protein Information
potassium voltage-gated channel subfamily D member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily D member 1
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv4.1
UniProt Entry Name
KCND1_HUMAN
NCBI Summary for KCND1
This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013]
UniProt Comments for KCND1
KCND1: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.1/KCND1 sub-subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: integral to membrane; plasma membrane
Molecular Function: A-type (transient outward) potassium channel activity; delayed rectifier potassium channel activity
Research Articles on KCND1
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Pathways associated with KCND1 cdna clone
Diseases associated with KCND1 cdna clone
Organs/Tissues associated with KCND1 cdna clone
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