BC006367
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,229 Da
NCBI Official Full Name
Homo sapiens potassium voltage-gated channel, subfamily G, member 1, mRNA
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily G member 1
NCBI Protein Information
potassium voltage-gated channel subfamily G member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily G member 1
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv6.1; kH2
UniProt Entry Name
KCNG1_HUMAN
NCBI Summary for KCNG1
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNG1
Kv6.1: Probable potassium channel subunit. May need to associate with another protein to form a functional channel. May modulate channel activity. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.1/KCNG1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 20q13
Cellular Component: intracellular membrane-bound organelle; plasma membrane; voltage-gated potassium channel complex
Molecular Function: delayed rectifier potassium channel activity
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Pathways associated with KCNG1 cdna clone
Diseases associated with KCNG1 cdna clone
Organs/Tissues associated with KCNG1 cdna clone
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