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KDELR2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1271790 KDELR2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KDELR2, cDNA Clone

 Also Known As   

KDELR2 cDNA Clone

 Product Gene Name   

KDELR2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgaacattt tccggctgac tggggacctg tcccacctgg cggccatcgt catcctgctg ctgaagatct ggaagacgcg ctcctgcgcc ggtatttctg ggaaaagcca gcttctgttt gcactggtct tcacaactcg ttacctggat ctttttactt catttatttc attgtataac acatctatga aggttatcta ccttgcctgc tcctatgcca cagtgtacct gatctacctg aaatttaagg caacctacga tggaaatcat gataccttcc gagtggagtt tctggtggtc cctgtgggag gcctctcatt tttagttaat cacgatttct ctcctcttga gatcctctgg accttctcca tctacctgga gtccgtggct atccttccgc agctgtttgt gatcagcaag actggggagg ccgagaccat caccacccac tacctgttct tcctgggcct ctatcgtgct ttgtatcttg tcaactggat ctggcgcttc tactttgagg gcttctttga cctcattgct gtggtggccg gcgtagtcca gaccatccta tactgtgact tcttctactt gtacattaca aaagtactca agggaaagaa gctcagtttg ccagcataa
 OMIM    609024
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 Vector    pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of KDELR2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for KDELR2. It may not necessarily be applicable to this product.
 NCBI GI #    33869906
 NCBI GeneID    11014
 NCBI Accession #    BC012994 [Other Products]
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 UniProt Secondary Accession #    Q6IPC5; Q96E30; A4D2P4 [Other Products]
 UniProt Related Accession #    P33947 [Other Products]
 Molecular Weight    21,242 Da
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 NCBI Official Full Name    Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, mRNA
 NCBI Official Synonym Full Names    KDEL endoplasmic reticulum protein retention receptor 2
 NCBI Official Symbol    KDELR2 [Similar Products]
 NCBI Official Synonym Symbols   
ELP-1; ERD2.2
[Similar Products]
 NCBI Protein Information    ER lumen protein-retaining receptor 2
 UniProt Protein Name    ER lumen protein-retaining receptor 2
 UniProt Synonym Protein Names   
ERD2-like protein 1; ELP-1; KDEL endoplasmic reticulum protein retention receptor 2; KDEL receptor 2
 Protein Family    ER lumen protein-retaining receptor
 UniProt Gene Name    KDELR2 [Similar Products]
 UniProt Synonym Gene Names    ERD2.2; ELP-1; KDEL receptor 2 [Similar Products]
 UniProt Entry Name    ERD22_HUMAN
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 NCBI Summary for KDELR2    Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KDELR2    KDELR2: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L. Belongs to the ERD2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7p22.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; transport vesicle

Molecular Function: KDEL sequence binding

Biological Process: intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER
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 Research Articles on KDELR2    1. A Golgi-based KDELR-dependent signalling pathway controls invadopodia-dependent extracellular matrix degradation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with KDELR2 cdna cloneDiseases associated with KDELR2 cdna clone
 Products by Pathway  Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >1 publications with KDELR2 and Hepatitis
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