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KRT18 cdna clone

Scan QR to view Datasheet Catalog #    MBS1265669 KRT18 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KRT18, cDNA Clone

★Popular Item★
 Also Known As   

KRT18 cDNA Clone

 Product Gene Name   

KRT18 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgagcttca ccactcgctc caccttctcc accaactacc ggtccctggg ctctgtccag gcgcccagct acggcgcccg gccggtcagc agcgcggcca gcgtctatgc aggcgctggg ggctctggtt cccggatctc cgtgtcccgc tccaccagct tcaggggcgg catggggtcc gggggcctgg ccaccgggat agccgggggt ctggcaggaa tgggaggcat ccagaacgag aaggagacca tgcaaagcct gaacgaccgc ctggcctctt acctggacag agtgaggagc ctggagaccg agaaccggag gctggagagc aaaatccggg agcacttgga gaagaaggga ccccaggtca gagactggag ccattacttc aagatcatcg aggacctgag ggctcagatc ttcgcaaata ctgtggacaa tgcccgcatc gttctgcaga ttgacaatgc ccgtcttgct gctgatgact ttagagtcaa gtatgagaca gagctggcca tgcgccagtc tgtggagaac gacatccatg ggctccgcaa ggtcattgat gacaccaata tcacacgact gcagctggag acagagatcg aggctctcaa ggaggagctg ctcttcatga agaagaacca cgaagaggaa gtaaaaggcc tacaagccca gattgccagc tctgggttga ccgtggaggt agatgccccc aaatctcagg acctcgccaa gatcatggca gacatccggg cccaatatga cgagctggct cggaagaacc gagaggagct agacaagtac tggtctcagc agattgagga gagcaccaca gtggtcacca cacagtctgc tgaggttgga gctgctgaga cgacgctcac agagctgaga cgtacagtcc agtccttgga gatcgacctg gactccatga gaaatctgaa ggccagcttg gagaacagcc tgagggaggt ggaggcccgc tacgccctac agatggagca gctcaacggg atcctgctgc accttgagtc agagctggca cagacccggg cagagggaca gcgccaggcc caggagtatg aggccctgct gaacatcaag gtcaagctgg aggctgagat cgccacctac cgccgcctgc tggaagatgg cgaggacttt aatcttggtg atgccttgga cagcagcaac tccatgcaaa ccatccaaaa gaccaccacc cgccggatag tggatggcaa agtggtgtct gagaccaatg acaccaaagt tctgaggcat taa
 OMIM    148070
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of KRT18 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for KRT18. It may not necessarily be applicable to this product.
 NCBI GI #    13111814
 NCBI GeneID    3875
 NCBI Accession #    BC000180 [Other Products]
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 UniProt Secondary Accession #    Q53G38; Q5U0N8; Q9BW26 [Other Products]
 UniProt Related Accession #    P05783 [Other Products]
 Molecular Weight    48,058 Da
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 NCBI Official Full Name    Homo sapiens keratin 18, mRNA
 NCBI Official Synonym Full Names    keratin 18
 NCBI Official Symbol    KRT18 [Similar Products]
 NCBI Official Synonym Symbols   
K18; CK-18; CYK18
[Similar Products]
 NCBI Protein Information    keratin, type I cytoskeletal 18
 UniProt Protein Name    Keratin, type I cytoskeletal 18
 UniProt Synonym Protein Names   
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
 Protein Family    Keratin
 UniProt Gene Name    KRT18 [Similar Products]
 UniProt Synonym Gene Names    CYK18; CK-18; K18 [Similar Products]
 UniProt Entry Name    K1C18_HUMAN
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 NCBI Summary for KRT18    KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KRT18    K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.

Protein type: Nucleolus; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: cell-cell adherens junction; cytoplasm; intermediate filament; keratin filament; microtubule organizing center

Molecular Function: protein binding

Biological Process: anatomical structure morphogenesis; Golgi to plasma membrane CFTR protein transport; intermediate filament cytoskeleton organization and biogenesis; negative regulation of apoptosis

Disease: Cirrhosis, Familial
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 Research Articles on KRT18    1. NAFLD patients, serum CK-18 levels reflect disease activity scores and correlate with histological changes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with KRT18 cdna cloneDiseases associated with KRT18 cdna clone
 Products by Pathway  Pathway Diagram
 Caspase Cascade In Apoptosis Pathway antibodies  Caspase Cascade In Apoptosis Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >43 publications with KRT18 and Neoplasms
 Liver Diseases Antibodies  >28 publications with KRT18 and Liver Diseases
 Carcinoma Antibodies  >25 publications with KRT18 and Carcinoma
 Breast Neoplasms Antibodies  >13 publications with KRT18 and Breast Neoplasms
 Adenocarcinoma Antibodies  >13 publications with KRT18 and Adenocarcinoma
 Fibrosis Antibodies  >12 publications with KRT18 and Fibrosis
 Neoplasm Metastasis Antibodies  >9 publications with KRT18 and Neoplasm Metastasis
 Fatty Liver Antibodies  >9 publications with KRT18 and Fatty Liver
 Liver Cirrhosis Antibodies  >8 publications with KRT18 and Liver Cirrhosis
 Liver Neoplasms Antibodies  >7 publications with KRT18 and Liver Neoplasms
Organs/Tissues associated with KRT18 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >34 publications with KRT18 and Liver
 Blood Antibodies  >18 publications with KRT18 and Blood
 Eye Antibodies  >6 publications with KRT18 and Eye
 Muscle Antibodies  >6 publications with KRT18 and Muscle
 Kidney Antibodies  >6 publications with KRT18 and Kidney
 Prostate Antibodies  >5 publications with KRT18 and Prostate
 Lymph Antibodies  >5 publications with KRT18 and Lymph
 Lymph Node Antibodies  >5 publications with KRT18 and Lymph Node
 Stomach Antibodies  >5 publications with KRT18 and Stomach
 Vascular Antibodies  >4 publications with KRT18 and Vascular
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