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LAMP2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1275848 LAMP2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LAMP2, cDNA Clone

★Popular Item★
 Also Known As   

LAMP2 cDNA Clone

 Product Gene Name   

LAMP2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggtgtgct tccgcctctt cccggttccg ggctcagggc tcgttctggt ctgcctagtc ctgggagctg tgcggtctta tgcattggaa cttaatttga cagattcaga aaatgccact tgcctttatg caaaatggca gatgaatttc acagttcgct atgaaactac aaataaaact tataaaactg taaccatttc agaccatggc actgtgacat ataatggaag catttgtggg gatgatcaga atggtcccaa aatagcagtg cagttcggac ctggcttttc ctggattgcg aattttacca aggcagcatc tacttattca attgacagcg tctcattttc ctacaacact ggtgataaca caacatttcc tgatgctgaa gataaaggaa ttcttactgt tgatgaactt ttggccatca gaattccatt gaatgacctt tttagatgca atagtttatc aactttggaa aagaatgatg ttgtccaaca ctactgggat gttcttgtac aagcttttgt ccaaaatggc acagtgagca caaatgagtt cctgtgtgat aaagacaaaa cttcaacagt ggcacccacc atacacacca ctgtgccatc tcctactaca acacctactc caaaggaaaa accagaagct ggaacctatt cagttaataa tggcaatgat acttgtctgc tggctaccat ggggctgcag ctgaacatca ctcaggataa ggttgcttca gttattaaca tcaaccccaa tacaactcac tccacaggca gctgccgttc tcacactgct ctacttagac tcaatagcag caccattaag tatctagact ttgtctttgc tgtgaaaaat gaaaaccgat tttatctgaa ggaagtgaac atcagcatgt atttggttaa tggctccgtt ttcagcattg caaataacaa tctcagctac tgggatgccc ccctgggaag ttcttatatg tgcaacaaag agcagactgt ttcagtgtct ggagcatttc agataaatac ctttgatcta agggttcagc ctttcaatgt gacacaagga aagtattcta cagcccaaga gtgttcgctg gatgatgaca ccattctaat cccaattata gttggtgctg gtctttcagg cttgattatc gttatagtga ttgcttacgt aattggcaga agaaaaagtt atgctggata tcagactctg taa
 OMIM    300257
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LAMP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for LAMP2. It may not necessarily be applicable to this product.
 NCBI GI #    12804214
 NCBI GeneID    3920
 NCBI Accession #    BC002965 [Other Products]
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 UniProt Secondary Accession #    Q16641; Q6Q3G8; Q96J30; Q99534; Q9UD93; A8K4X5; D3DTF0 [Other Products]
 UniProt Related Accession #    P13473 [Other Products]
 Molecular Weight    45,170 Da
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 NCBI Official Full Name    Homo sapiens lysosomal-associated membrane protein 2, mRNA
 NCBI Official Synonym Full Names    lysosomal associated membrane protein 2
 NCBI Official Symbol    LAMP2 [Similar Products]
 NCBI Official Synonym Symbols   
LAMPB; CD107b; LAMP-2; LGP110
[Similar Products]
 NCBI Protein Information    lysosome-associated membrane glycoprotein 2
 UniProt Protein Name    Lysosome-associated membrane glycoprotein 2
 UniProt Synonym Protein Names   
CD107 antigen-like family member B; CD_antigen: CD107b
 Protein Family    Lysosome-associated membrane glycoprotein
 UniProt Gene Name    LAMP2 [Similar Products]
 UniProt Synonym Gene Names    LAMP-2; Lysosome-associated membrane protein 2 [Similar Products]
 UniProt Entry Name    LAMP2_HUMAN
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 NCBI Summary for LAMP2    The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LAMP2    LAMP2: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Defects in LAMP2 are the cause of Danon disease (DAND); also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes. Belongs to the LAMP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: extracellular space; late endosome; late endosome membrane; lysosomal lumen; lysosomal membrane; lysosome; membrane; plasma membrane; platelet dense granule membrane

Molecular Function: enzyme binding; protein binding

Biological Process: platelet degranulation; protein import; protein stabilization; regulation of protein stability

Disease: Danon Disease
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 Research Articles on LAMP2    1. LAMP-2C serves as a natural inhibitor of chaperone-mediated autophagy that can selectively skew MHCII presentation of cytoplasmic antigens
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LAMP2 cdna cloneDiseases associated with LAMP2 cdna clone
 Products by Pathway  Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiomyopathies Antibodies  >54 publications with LAMP2 and Cardiomyopathies
 Glycogen Storage Disease Type IIb Antibodies  >41 publications with LAMP2 and Glycogen Storage Disease Type IIb
 Hypertrophy Antibodies  >21 publications with LAMP2 and Hypertrophy
 Neoplasms Antibodies  >20 publications with LAMP2 and Neoplasms
 Kidney Diseases Antibodies  >8 publications with LAMP2 and Kidney Diseases
 Inflammation Antibodies  >8 publications with LAMP2 and Inflammation
 Drug Toxicity Antibodies  >7 publications with LAMP2 and Drug Toxicity
 Liver Diseases Antibodies  >6 publications with LAMP2 and Liver Diseases
 Congenital Abnormalities Antibodies  >6 publications with LAMP2 and Congenital Abnormalities
 Fibrosis Antibodies  >4 publications with LAMP2 and Fibrosis
Organs/Tissues associated with LAMP2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >50 publications with LAMP2 and Muscle
 Blood Antibodies  >39 publications with LAMP2 and Blood
 Heart Antibodies  >38 publications with LAMP2 and Heart
 Brain Antibodies  >25 publications with LAMP2 and Brain
 Liver Antibodies  >21 publications with LAMP2 and Liver
 Nerve Antibodies  >17 publications with LAMP2 and Nerve
 Vascular Antibodies  >11 publications with LAMP2 and Vascular
 Kidney Antibodies  >10 publications with LAMP2 and Kidney
 Skin Antibodies  >9 publications with LAMP2 and Skin
 Lung Antibodies  >8 publications with LAMP2 and Lung
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