BC069650
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,491 Da
NCBI Official Full Name
Homo sapiens lymphocyte transmembrane adaptor 1, mRNA
NCBI Official Synonym Full Names
lymphocyte transmembrane adaptor 1
NCBI Official Synonym Symbols
NCBI Protein Information
lymphocyte transmembrane adapter 1
UniProt Protein Name
Lymphocyte transmembrane adapter 1
UniProt Synonym Protein Names
Linker for activation of X cells; Membrane-associated adapter protein LAX
UniProt Synonym Gene Names
UniProt Entry Name
LAX1_HUMAN
UniProt Comments for LAX1
LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; lipid raft; membrane; plasma membrane
Molecular Function: protein binding; protein kinase binding; SH2 domain binding
Biological Process: B cell activation; immune response; inactivation of MAPK activity; negative regulation of T cell activation
Research Articles on LAX1
Precautions
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Disclaimer
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Diseases associated with LAX1 cdna clone
Organs/Tissues associated with LAX1 cdna clone
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