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LDHA cdna clone

Scan QR to view Datasheet Catalog #    MBS1270637 LDHA cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LDHA, cDNA Clone

 Also Known As   

LDHA cDNA Clone

 Product Gene Name   

LDHA cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggcaactc taaaggatca gctgatttat aatcttctaa aggaagaaca gaccccccag aataagatta cagttgttgg ggttggtgct gttggcatgg cctgtgccat cagtatctta atgaaggact tggcagatga acttgctctt gttgatgtca tcgaagacaa attgaaggga gagatgatgg atctccaaca tggcagcctt ttccttagaa caccaaagat tgtctctggc aaagactata atgtaactgc aaactccaag ctggtcatta tcacggctgg ggcacgtcag caagagggag aaagccgtct taatttggtc cagcgtaacg tgaacatctt taaattcatc attcctaatg ttgtaaaata cagcccgaac tgcaagttgc ttattgtttc aaatccagtg gatatcttga cctacgtggc ttggaagata agtggttttc ccaaaaaccg tgttattgga agtggttgca atctggattc agcccgattc cgttacctga tgggggaaag gctgggagtt cacccattaa gctgtcatgg gtgggtcctt ggggaacatg gagattccag tgtgcctgta tggagtggaa tgaatgttgc tggtgtctct ctgaagactc tgcacccaga tttagggact gataaagata aggaacagtg gaaagaggtt cacaagcagg tggttgagag tgcttatgag gtgatcaaac tcaaaggcta cacatcctgg gctattggac tctctgtagc agatttggca gagagtataa tgaagaatct taggcgggtg cacccagttt ccaccatgat taagggtctt tacggaataa aggatgatgt cttccttagt gttccttgca ttttgggaca gaatggaatc tcagaccttg tgaaggtgac tctgacttct gaggaagagg cccgtttgaa gaagagtgca gatacacttt gggggatcca aaaggagctg caattttaa
 OMIM    150000
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LDHA cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for LDHA. It may not necessarily be applicable to this product.
 NCBI GI #    45501321
 NCBI GeneID    3939
 NCBI Accession #    BC067223 [Other Products]
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 UniProt Secondary Accession #    Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9; B4DKQ2; B7Z5E3; D3DQY3; F8W819 [Other Products]
 UniProt Related Accession #    P00338 [Other Products]
 Molecular Weight    26,712 Da
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 NCBI Official Full Name    Homo sapiens lactate dehydrogenase A, mRNA
 NCBI Official Synonym Full Names    lactate dehydrogenase A
 NCBI Official Symbol    LDHA [Similar Products]
 NCBI Official Synonym Symbols   
LDHM; GSD11; PIG19; HEL-S-133P
[Similar Products]
 NCBI Protein Information    L-lactate dehydrogenase A chain
 UniProt Protein Name    L-lactate dehydrogenase A chain
 UniProt Synonym Protein Names   
Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
 Protein Family    L-lactate dehydrogenase
 UniProt Gene Name    LDHA [Similar Products]
 UniProt Synonym Gene Names    LDH-A; LDH-M [Similar Products]
 UniProt Entry Name    LDHA_HUMAN
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 NCBI Summary for LDHA    The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
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 UniProt Comments for LDHA    LDH-A: Homotetramer. Belongs to the LDH/MDH superfamily. LDH family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - cysteine and methionine; Apoptosis; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC 1.1.1.27; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: cell-cell adherens junction; cytosol; membrane; nucleus

Molecular Function: L-lactate dehydrogenase activity; protein binding

Biological Process: pyruvate metabolic process

Disease: Glycogen Storage Disease Xi
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 Research Articles on LDHA    1. Multivariable analysis showed that combined expression of pyruvate kinase type M2 and lactate dehydrogenase A was an independent poor prognostic marker for survival.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LDHA cdna cloneDiseases associated with LDHA cdna clone
 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >48 publications with LDHA and Neoplasms
 Adenocarcinoma Antibodies  >10 publications with LDHA and Adenocarcinoma
 Nervous System Diseases Antibodies  >8 publications with LDHA and Nervous System Diseases
 Breast Neoplasms Antibodies  >8 publications with LDHA and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >6 publications with LDHA and Cell Transformation, Neoplastic
 Liver Neoplasms Antibodies  >5 publications with LDHA and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with LDHA and Carcinoma, Hepatocellular
 Brain Diseases Antibodies  >5 publications with LDHA and Brain Diseases
 Cardiovascular Diseases Antibodies  >5 publications with LDHA and Cardiovascular Diseases
 Liver Diseases Antibodies  >5 publications with LDHA and Liver Diseases
Organs/Tissues associated with LDHA cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >24 publications with LDHA and Blood
 Testis Antibodies  >18 publications with LDHA and Testis
 Muscle Antibodies  >17 publications with LDHA and Muscle
 Vascular Antibodies  >15 publications with LDHA and Vascular
 Brain Antibodies  >11 publications with LDHA and Brain
 Liver Antibodies  >9 publications with LDHA and Liver
 Heart Antibodies  >8 publications with LDHA and Heart
 Ovary Antibodies  >6 publications with LDHA and Ovary
 Kidney Antibodies  >6 publications with LDHA and Kidney
 Bone Antibodies  >5 publications with LDHA and Bone
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