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LRRFIP1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1270649 LRRFIP1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LRRFIP1, cDNA Clone

★Popular Item★
 Also Known As   

LRRFIP1 cDNA Clone

 Product Gene Name   

LRRFIP1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atgcatgtaa tggacctaca aagggatgcc aacagacaga tcagcgacct caaatttaaa cttgcaaaat ctgagcaaga gataactgca ttagaacaaa atgtaataag gttagagagt caagtatcac gttacaaatc agcggctgaa aatgcagaaa aaatagaaga tgaacttaag gcagaaaaac ggaaactcca aagagagctc cgctctgcat tggataaaac agaagagctc gaggtgagca acggccactt agtgaagcgt ctggaaaaaa tgaaagcaaa tcggagtgca ctcttgtccc agcagtaa
 OMIM    603256
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 Vector    pENTR223.1
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LRRFIP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for LRRFIP1. It may not necessarily be applicable to this product.
 NCBI GI #    14715004
 NCBI GeneID    9208
 NCBI Accession #    BC010662 [Other Products]
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 UniProt Secondary Accession #    O75766; O75799; Q32MZ5; Q53T49; Q6PKG2; Q9Y607; E9PGZ2 [Other Products]
 UniProt Related Accession #    Q32MZ4 [Other Products]
 Molecular Weight    73,060 Da
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 NCBI Official Full Name    Homo sapiens leucine rich repeat (in FLII) interacting protein 1, mRNA
 NCBI Official Synonym Full Names    LRR binding FLII interacting protein 1
 NCBI Official Symbol    LRRFIP1 [Similar Products]
 NCBI Official Synonym Symbols   
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
[Similar Products]
 NCBI Protein Information    leucine-rich repeat flightless-interacting protein 1
 UniProt Protein Name    Leucine-rich repeat flightless-interacting protein 1
 UniProt Synonym Protein Names   
GC-binding factor 2; TAR RNA-interacting protein
 Protein Family    Leucine-rich repeat flightless-interacting protein
 UniProt Gene Name    LRRFIP1 [Similar Products]
 UniProt Synonym Gene Names    GCF2; TRIP; LRR FLII-interacting protein 1 [Similar Products]
 UniProt Entry Name    LRRF1_HUMAN
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 UniProt Comments for LRRFIP1    LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cell-cell adherens junction; cytoplasm; cytoskeleton; cytosol; plasma membrane

Molecular Function: DNA binding; double-stranded RNA binding; protein binding; protein homodimerization activity

Biological Process: positive regulation of interferon type I production; regulation of transcription from RNA polymerase II promoter
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 Research Articles on LRRFIP1    1. Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/beta-catenin signaling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LRRFIP1 cdna cloneDiseases associated with LRRFIP1 cdna clone
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Signaling By FGFR In Disease Pathway antibodies  Signaling By FGFR In Disease Pathway Diagram
 Signaling By FGFR Mutants Pathway antibodies  Signaling By FGFR Mutants Pathway Diagram
 Signaling By FGFR1 Fusion Mutants Pathway antibodies  Signaling By FGFR1 Fusion Mutants Pathway Diagram
 Signaling By FGFR1 Mutants Pathway antibodies  Signaling By FGFR1 Mutants Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with LRRFIP1 and Cardiovascular Diseases
 Neoplasms Antibodies  >4 publications with LRRFIP1 and Neoplasms
 Inflammation Antibodies  >3 publications with LRRFIP1 and Inflammation
 Heart Diseases Antibodies  >2 publications with LRRFIP1 and Heart Diseases
 Necrosis Antibodies  >2 publications with LRRFIP1 and Necrosis
 Death Antibodies  >1 publications with LRRFIP1 and Death
 Breast Neoplasms Antibodies  >1 publications with LRRFIP1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with LRRFIP1 and Nervous System Diseases
 Arteriosclerosis Antibodies  >1 publications with LRRFIP1 and Arteriosclerosis
 Hypertrophy Antibodies  >1 publications with LRRFIP1 and Hypertrophy
Organs/Tissues associated with LRRFIP1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with LRRFIP1 and Blood
 Heart Antibodies  >3 publications with LRRFIP1 and Heart
 Brain Antibodies  >3 publications with LRRFIP1 and Brain
 Adipose Tissue Antibodies  >2 publications with LRRFIP1 and Adipose Tissue
 Muscle Antibodies  >2 publications with LRRFIP1 and Muscle
 Testis Antibodies  >1 publications with LRRFIP1 and Testis
 Bone Marrow Antibodies  >1 publications with LRRFIP1 and Bone Marrow
 Bone Antibodies  >1 publications with LRRFIP1 and Bone
 Liver Antibodies  >1 publications with LRRFIP1 and Liver
 Nerve Antibodies  >1 publications with LRRFIP1 and Nerve
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