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MAS1 cdna clone

Scan QR to view Datasheet Catalog #    MBS1267205 MAS1 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MAS1, cDNA Clone

★Popular Item★
 Also Known As   

MAS1 cDNA Clone

 Product Gene Name   

MAS1 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggatgggt caaacgtgac atcatttgtt gttgaggaac ccacgaacat ctcaactggc aggaacgcct cagtcgggaa tgcacatcgg caaatcccca tcgtgcactg ggtcattatg agcatctccc cagtggggtt tgttgagaat gggattctcc tctggttcct gtgcttccgg atgagaagaa atcccttcac tgtctacatc acccacctgt ctatcgcaga catctcactg ctcttctgta ttttcatctt gtctatcgac tatgctttag attatgagct ttcttctggc cattactaca caattgtcac attatcagtg acttttctgt ttggctacaa cacgggcctc tatctgctga cggccattag tgtggagagg tgcctgtcag tcctttaccc catctggtac cgatgccatc gccccaagta ccagtcggca ttggtctgtg cccttctgtg ggctctttct tgcttggtga ccaccatgga gtatgtcatg tgcatcgaca gagaagaaga gagtcactct cggaatgact gccgagcagt catcatcttt atagccatcc tgagcttcct ggtcttcacg cccctcatgc tggtgtccag caccatcttg gtcgtgaaga tccggaagaa cacgtgggct tcccattcct ccaagcttta catagtcatc atggtcacca tcattatatt cctcatcttc gctatgccca tgagactcct ttacctgctg tactatgagt attggtcgac ctttgggaac ctacaccaca tttccctgct cttctccaca atcaacagta gcgccaaccc tttcatttac ttctttgtgg gaagcagtaa gaagaagaga ttcaaggagt ccttaaaagt tgttctgacc agggctttca aagatgaaat gcaacctcgg cgccagaaag acaattgtaa tacggtcaca gttgagactg tcgtctaa
 Chromosome Location    Chromosome: 6; NC_000006.11 (160327974..160329108). Location: 6q25.3-q26
 OMIM    165180
 3D Structure    ModBase 3D Structure for P04201
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of MAS1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for MAS1. It may not necessarily be applicable to this product.
 NCBI GI #    47481159
 NCBI GeneID    4142
 NCBI Accession #    BC069581 [Other Products]
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 UniProt Primary Accession #    P04201 [Other Products]
 UniProt Secondary Accession #    Q2TBC9; Q6FG47; E1P5B3 [Other Products]
 UniProt Related Accession #    P04201 [Other Products]
 Molecular Weight    37,465 Da
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 NCBI Official Full Name    Homo sapiens MAS1 oncogene, mRNA
 NCBI Official Synonym Full Names    MAS1 oncogene
 NCBI Official Symbol    MAS1 [Similar Products]
 NCBI Official Synonym Symbols   
MAS
[Similar Products]
 NCBI Protein Information    proto-oncogene Mas
 UniProt Protein Name    Proto-oncogene Mas
 Protein Family    Proto-oncogene
 UniProt Gene Name    MAS1 [Similar Products]
 UniProt Synonym Gene Names    MAS [Similar Products]
 UniProt Entry Name    MAS_HUMAN
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 NCBI Summary for MAS1    This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]
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 UniProt Comments for MAS1    MAS1: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Oncoprotein

Chromosomal Location of Human Ortholog: 6q25.3-q26

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; angiotensin type II receptor activity; peptide hormone binding; peptide binding; angiotensin receptor activity

Biological Process: response to drug; anatomical structure morphogenesis; hippocampus development; male gonad development; activation of NF-kappaB-inducing kinase; cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of protein amino acid phosphorylation; positive regulation of cell proliferation; regulation of inflammatory response; spermatogenesis; response to activity; positive regulation of DNA replication
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 Research Articles on MAS1    1. MasR was significantly upregulated in colon adenocarcinoma compared with non-neoplastic colon mucosa, which showed little or no expression of it. ACE gene expression and enzymatic activity were also increased in the tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MAS1 cdna cloneDiseases associated with MAS1 cdna clone
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with MAS1 and Fibrosis
 Drug Toxicity Antibodies  >1 publications with MAS1 and Drug Toxicity
 Disease Models, Animal Antibodies  >1 publications with MAS1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >1 publications with MAS1 and Nervous System Diseases
 Heart Diseases Antibodies  >1 publications with MAS1 and Heart Diseases
 Inflammation Antibodies  >1 publications with MAS1 and Inflammation
 Hypertension Antibodies  >1 publications with MAS1 and Hypertension
Organs/Tissues associated with MAS1 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >1 publications with MAS1 and Mixed
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