BC028355
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,709 Da
NCBI Official Full Name
Homo sapiens Mdm1 nuclear protein homolog (mouse), mRNA
NCBI Official Synonym Full Names
Mdm1 nuclear protein
NCBI Protein Information
nuclear protein MDM1
UniProt Protein Name
Nuclear protein MDM1
UniProt Entry Name
MDM1_HUMAN
NCBI Summary for MDM1
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
UniProt Comments for MDM1
MDM1: a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: centriole; centrosome; nucleus
Molecular Function: microtubule binding
Biological Process: negative regulation of centriole replication; retina development in camera-type eye
Research Articles on MDM1
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Diseases associated with MDM1 cdna clone
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