BC013081
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
6,927 Da
NCBI Official Full Name
Homo sapiens metallothionein 3, mRNA
NCBI Official Synonym Full Names
metallothionein 3
NCBI Protein Information
metallothionein-3
UniProt Protein Name
Metallothionein-3
UniProt Synonym Protein Names
GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III
UniProt Synonym Gene Names
UniProt Entry Name
MT3_HUMAN
UniProt Comments for MT3
MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family.
Chromosomal Location of Human Ortholog: 16q13
Cellular Component: cytoplasm; cytosol; inclusion body; intracellular; perinuclear region of cytoplasm; synaptic vesicle
Molecular Function: cadmium ion binding; caspase inhibitor activity; copper ion binding; drug binding; protein binding; protein kinase activator activity; zinc ion binding
Biological Process: activation of protein kinase B; astrocyte development; cadmium ion homeostasis; cell proliferation; cellular lipid catabolic process; cellular metal ion homeostasis; cellular zinc ion homeostasis; cholesterol catabolic process; energy reserve metabolic process; histone modification; leptin-mediated signaling pathway; negative regulation of apoptosis; negative regulation of autophagy; negative regulation of axon extension; negative regulation of caspase activity; negative regulation of cell growth; negative regulation of neuron apoptosis; negative regulation of oxidoreductase activity; negative regulation of transcription, DNA-dependent; positive regulation of catalytic activity; positive regulation of protein amino acid phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein import into nucleus, translocation; protein kinase B signaling cascade; protein stabilization; regulation of protein amino acid glycosylation; regulation of response to food; removal of superoxide radicals; response to hypoxia; response to metal ion; zinc ion homeostasis; zinc ion transport
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Diseases associated with MT3 cdna clone
Organs/Tissues associated with MT3 cdna clone
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