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NAPSA cdna clone

Scan QR to view Datasheet Catalog #    MBS1268692 NAPSA cdna clone
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


 Also Known As   


 Product Gene Name   

NAPSA cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    Please Inquire
 OMIM    605631
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 Vector    Please Inquire
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NAPSA cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NAPSA. It may not necessarily be applicable to this product.
 NCBI GI #    17389632
 NCBI GeneID    9476
 NCBI Accession #    BC017842 [Other Products]
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 UniProt Secondary Accession #    Q8WWD9 [Other Products]
 UniProt Related Accession #    O96009 [Other Products]
 Molecular Weight    45,387 Da
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 NCBI Official Full Name    Homo sapiens napsin A aspartic peptidase, mRNA
 NCBI Official Synonym Full Names    napsin A aspartic peptidase
 NCBI Official Symbol    NAPSA [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    napsin-A
 UniProt Protein Name    Napsin-A
 UniProt Synonym Protein Names   
Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02
 Protein Family    Napsin
 UniProt Gene Name    NAPSA [Similar Products]
 UniProt Synonym Gene Names    NAP1; NAPA; ASP4; Asp 4 [Similar Products]
 UniProt Entry Name    NAPSA_HUMAN
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 NCBI Summary for NAPSA    This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
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 UniProt Comments for NAPSA    NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.

Protein type: EC 3.4.23.-; Secreted, signal peptide; Protease; Secreted

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; lysosome

Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity

Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; surfactant homeostasis
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 Research Articles on NAPSA    1. The immunocytochemical expressions of napsin A and p40 in imprint cytology seem to be of great utility for the accurate histological differentiation of lung cancers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NAPSA cdna cloneDiseases associated with NAPSA cdna clone
 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >42 publications with NAPSA and Neoplasms
 Pleural Effusion Antibodies  >6 publications with NAPSA and Pleural Effusion
 Kidney Diseases Antibodies  >5 publications with NAPSA and Kidney Diseases
 Breast Neoplasms Antibodies  >5 publications with NAPSA and Breast Neoplasms
 Liver Neoplasms Antibodies  >3 publications with NAPSA and Liver Neoplasms
 Fibrosis Antibodies  >3 publications with NAPSA and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >2 publications with NAPSA and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with NAPSA and Liver Diseases
 Skin Neoplasms Antibodies  >1 publications with NAPSA and Skin Neoplasms
 Disease Models, Animal Antibodies  >1 publications with NAPSA and Disease Models, Animal
Organs/Tissues associated with NAPSA cdna clone
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >47 publications with NAPSA and Lung
 Kidney Antibodies  >15 publications with NAPSA and Kidney
 Spleen Antibodies  >2 publications with NAPSA and Spleen
 Prostate Antibodies  >2 publications with NAPSA and Prostate
 Uterus Antibodies  >1 publications with NAPSA and Uterus
 Trachea Antibodies  >1 publications with NAPSA and Trachea
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