View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List NAT1 cdna clone Catalog # MBS1267942 Unit / Price 0.01 mg Plasmid + 0.2 mL Glycerol-Stock / $205 +1 FREE 8GB USB 5x0.01 mg Plasmid + 5x0.2 mL Glycerol-Stock / $915 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name NAT1, cDNA Clone Popular Item Full Product Name NAT1 cDNA Clone Product Gene Name NAT1 cdna clone[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence atggacattg aagcatatct tgaaagaatt ggctataaga agtctaggaa caaattggac ttggaaacat taactgacat tcttcaacac cagatccgag ctgttccctt tgagaacctt aacatccatt gtggggatgc catggactta ggcttagagg ccatttttga tcaagttgtg agaagaaatc ggggtggatg gtgtctccag gtcaatcatc ttctgtactg ggctctgacc actattggtt ttgagaccac gatgttggga gggtatgttt acagcactcc agccaaaaaa tacagcactg gcatgattca ccttctcctg caggtgacca ttgatggcag gaactacatt gtcgatgctg ggtttggacg ctcataccag atgtggcagc ctctggagtt aatttctggg aaggatcagc ctcaggtgcc ttgtgtcttc cgtttgacgg aagagaatgg attctggtat ctagaccaaa tcagaaggga acagtacatt ccaaatgaag aatttcttca ttctgatctc ctagaagaca gcaaataccg aaaaatctac tcctttactc ttaagcctcg aacaattgaa gattttgagt ctatgaatac atacctgcag acatctccat catctgtgtt tactagtaaa tcattttgtt ccttgcagac cccagatggg gttcactgtt tggtgggctt caccctcacc cataggagat tcaattataa ggacaataca gatctaatag agttcaagac tctgagtgag gaagaaatag aaaaagtgct gaaaaatata tttaatattt ccttgcagag aaagcttgtg cccaaacatg gtgatagatt ttttactatt tag OMIM 108345 Vector pENTR223.1 Clone Sequence Report Provided with product shipment ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of NAT1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for NAT1. It may not necessarily be applicable to this product. NCBI GI # 28838335 NCBI GeneID 9 NCBI Accession # BC047666 [Other Products] UniProt Secondary Accession # O15159; O15300; Q546N1; Q96TE9; A8K4E7[Other Products] UniProt Related Accession # P18440[Other Products] Molecular Weight 33,899 Da TOP NCBI Official Full Name Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase), mRNA NCBI Official Synonym Full Names N-acetyltransferase 1 NCBI Official Symbol NAT1 [Similar Products] NCBI Official Synonym Symbols AAC1; MNAT; NATI; NAT-1 [Similar Products] NCBI Protein Information arylamine N-acetyltransferase 1 UniProt Protein Name Arylamine N-acetyltransferase 1 UniProt Synonym Protein Names Arylamide acetylase 1; Monomorphic arylamine N-acetyltransferase; MNAT; N-acetyltransferase type 1; NAT-1 Protein Family Nucleobase-ascorbate transporter UniProt Gene Name NAT1 [Similar Products] UniProt Synonym Gene Names AAC1; MNAT; NAT-1 [Similar Products] UniProt Entry Name ARY1_HUMAN TOP NCBI Summary for NAT1 This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] TOP UniProt Comments for NAT1 NAT1: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.Protein type: Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase; EC 2.3.1.5; Secondary Metabolites Metabolism - caffeineChromosomal Location of Human Ortholog: 8p22Cellular Component: cytosolMolecular Function: arylamine N-acetyltransferase activityBiological Process: xenobiotic metabolic process Research Articles on NAT1 1. The rs1799931(G>A) genotype was detected in the control population but not in the T2DM population. The wild type (G) allele frequency was higher in T2DM than controls. The mutant allele (A) in rs1799931(G>A) had a protective effect for T2DM. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with NAT1 cdna clone Products by Pathway Pathway Diagram Acetylation Pathway antibodies Acetylation Pathway Diagram Arylamine Metabolism Pathway antibodies Arylamine Metabolism Pathway Diagram Biological Oxidations Pathway antibodies Biological Oxidations Pathway Diagram Caffeine Metabolism Pathway antibodies Caffeine Metabolism Pathway Diagram Caffeine Metabolism Pathway antibodies Caffeine Metabolism Pathway Diagram Chemical Carcinogenesis Pathway antibodies Chemical Carcinogenesis Pathway Diagram Chemical Carcinogenesis Pathway antibodies Chemical Carcinogenesis Pathway Diagram Drug Metabolism - Other Enzymes Pathway antibodies Drug Metabolism - Other Enzymes Pathway Diagram Drug Metabolism - Other Enzymes Pathway antibodies Drug Metabolism - Other Enzymes Pathway Diagram Metabolism Pathway antibodies Metabolism Pathway Diagram Diseases associated with NAT1 cdna clone Disease Name Pubmed Publications Neoplasms Antibodies >226 publications with NAT1 and Neoplasms Drug Toxicity Antibodies >53 publications with NAT1 and Drug Toxicity Urinary Bladder Neoplasms Antibodies >44 publications with NAT1 and Urinary Bladder Neoplasms Breast Neoplasms Antibodies >41 publications with NAT1 and Breast Neoplasms Lung Neoplasms Antibodies >28 publications with NAT1 and Lung Neoplasms Lung Diseases Antibodies >24 publications with NAT1 and Lung Diseases Liver Neoplasms Antibodies >21 publications with NAT1 and Liver Neoplasms Liver Diseases Antibodies >13 publications with NAT1 and Liver Diseases Adenoma Antibodies >13 publications with NAT1 and Adenoma Prostatic Neoplasms Antibodies >12 publications with NAT1 and Prostatic Neoplasms Organs/Tissues associated with NAT1 cdna clone Organ/Tissue Name Pubmed Publications Liver Antibodies >108 publications with NAT1 and Liver Blood Antibodies >85 publications with NAT1 and Blood Lung Antibodies >52 publications with NAT1 and Lung Prostate Antibodies >35 publications with NAT1 and Prostate Intestine Antibodies >26 publications with NAT1 and Intestine Kidney Antibodies >24 publications with NAT1 and Kidney Stomach Antibodies >11 publications with NAT1 and Stomach Placenta Antibodies >9 publications with NAT1 and Placenta Pancreas Antibodies >6 publications with NAT1 and Pancreas Vascular Antibodies >5 publications with NAT1 and Vascular TOP © 2006-24 MyBioSource.com. 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