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NAT2 cdna clone

Scan QR to view Datasheet Catalog #    MBS1275478 NAT2 cdna clone
Unit / Price
0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NAT2, cDNA Clone

 Also Known As   

NAT2 cDNA Clone

 Product Gene Name   

NAT2 cdna clone

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Molecular Biology Protocol    Molecular Biology Protocol
 Frequently Asked Questions    Frequently Asked Questions
 Sequence    atggacattg aagcatattt tgaaagaatt ggctataaga actctaggaa caaattggac ttggaaacat taactgacat tcttgagcac cagatccggg ctgttccctt tgagaacctt aacatgcatt gtgggcaagc catggagttg ggcttagagg ctatttttga tcacattgta agaagaaacc ggggtgggtg gtgtctccag gtcaatcaac ttctgtactg ggctctgacc acaatcggtt ttcagaccac aatgttagga gggtattttt atatccctcc agttaacaaa tacagcactg gcatggttca ccttctcctg caggtgacca ttgacggcag gaattacatt gtcgatgctg ggtctggaag ctcctcccag atgtggcagc ctctagaatt aatttctggg aaggatcagc ctcaggtgcc ttgcattttc tgcttgacag aagagagagg aatctggtac ctggaccaaa tcaggagaga gcagtatatt acaaacaaag aatttcttaa ttctcatctc ctgccaaaga agaaacacca aaaaatatac ttatttacgc ttgaacctca aacaattgaa gattttgagt ctatgaatac atacctgcag acgtctccaa catcttcatt tataaccaca tcattttgtt ccttgcagac cccagaaggg gtttactgtt tggtgggctt catcctcacc tatagaaaat tcaattataa agacaataca gatctggtcg agtttaaaac tctcactgag gaagaggttg aagaagtgct gaaaaatata tttaagattt ccttggggag aaatctcgtg cccaaacctg gtgatggatc ccttactatt tag
 OMIM    243400
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 Vector    pENTR223.1 or pUC
 Clone Sequence Report    Provided with product shipment
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NAT2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NAT2. It may not necessarily be applicable to this product.
 NCBI GI #    16198419
 NCBI GeneID    10
 NCBI Accession #    BC015878 [Other Products]
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 UniProt Secondary Accession #    O43637; O60654; O60655; Q13146; Q16697; Q2MLE4; Q2MLF5; Q2MLG8; Q2MLJ6; Q2MLK4; Q2MLK6 [Other Products]
 UniProt Related Accession #    P11245 [Other Products]
 Molecular Weight    33,542 Da
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 NCBI Official Full Name    Homo sapiens N-acetyltransferase 2 (arylamine N-acetyltransferase), mRNA
 NCBI Official Synonym Full Names    N-acetyltransferase 2
 NCBI Official Symbol    NAT2 [Similar Products]
 NCBI Official Synonym Symbols   
AAC2; PNAT; NAT-2
[Similar Products]
 NCBI Protein Information    arylamine N-acetyltransferase 2
 UniProt Protein Name    Arylamine N-acetyltransferase 2
 UniProt Synonym Protein Names   
Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT
 Protein Family    N-terminal acetyltransferase
 UniProt Gene Name    NAT2 [Similar Products]
 UniProt Synonym Gene Names    AAC2; NAT-2; PNAT [Similar Products]
 UniProt Entry Name    ARY2_HUMAN
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 NCBI Summary for NAT2    This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]
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 UniProt Comments for NAT2    NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Secondary Metabolites Metabolism - caffeine; EC 2.3.1.5; Translation; Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity; protein binding

Biological Process: xenobiotic metabolic process

Disease: Acetylation, Slow
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 Research Articles on NAT2    1. Findings support a role for NAT2 in modifying the association between red meat consumption and colorectal cancer in Japanese and African Americans.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NAT2 cdna cloneDiseases associated with NAT2 cdna clone
 Products by Pathway  Pathway Diagram
 Acetylation Pathway antibodies  Acetylation Pathway Diagram
 Arylamine Metabolism Pathway antibodies  Arylamine Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >529 publications with NAT2 and Neoplasms
 Urinary Bladder Neoplasms Antibodies  >123 publications with NAT2 and Urinary Bladder Neoplasms
 Drug Toxicity Antibodies  >113 publications with NAT2 and Drug Toxicity
 Breast Neoplasms Antibodies  >77 publications with NAT2 and Breast Neoplasms
 Lung Neoplasms Antibodies  >57 publications with NAT2 and Lung Neoplasms
 Adenocarcinoma Antibodies  >44 publications with NAT2 and Adenocarcinoma
 Drug-Induced Liver Injury Antibodies  >41 publications with NAT2 and Drug-Induced Liver Injury
 Liver Neoplasms Antibodies  >41 publications with NAT2 and Liver Neoplasms
 Adenoma Antibodies  >39 publications with NAT2 and Adenoma
 Carcinoma, Squamous Cell Antibodies  >36 publications with NAT2 and Carcinoma, Squamous Cell
Organs/Tissues associated with NAT2 cdna clone
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >215 publications with NAT2 and Liver
 Intestine Antibodies  >37 publications with NAT2 and Intestine
 Bone Antibodies  >6 publications with NAT2 and Bone
 Connective Tissue Antibodies  >1 publications with NAT2 and Connective Tissue
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